Canaletto’s paintings open a new window on the relative sea-level rise in Venice     

Dario Camuffo 《Journal of Cultural Heritage》2001,2(4):92

The paintings by Canaletto (1697–1768), made with the help of a camera obscura, are just like real photographs, documenting as they do the Venice of the XVIII century with an accurate reproduction of all the details. The brown–green front left by the Laminaria, an alga living between the high and low tide, constitutes a precise biological indication of the average level of the high tide. By comparing the level of this front at Canaletto’s time with the present level, we can calculate/discover the relative sea level rise which has occurred in the last two and a half centuries.  相似文献   

Economic Evaluations, Partisanship, and Social Bases of Presidential Voting in Argentina, 1995 and 1999     

Canton  Dario; Jorrat  Jorge Raul 《Int. Journal of Public Opinion Research》2002,14(4):413-427

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Press releases and email notices increase local and global visibility of a small medical journal     

Dario Sambunjak 《Learned Publishing》2006,19(4):267-271

To increase its visibility among the general public and the international scientific community, the Croatian Medical Journal (CMJ), a small journal from the so‐called scientific periphery, introduced a media strategy of sending press releases to journalists and email notices to the newsdesk of a high‐profile international scientific journal. Subsequent news coverage and the positive response of journalists show that press releases and targeted email notices increased international visibility of articles published in a small scientific journal, and improved communication with journalists as mediators of scientific information to the general public.  相似文献   

Colorectal cancer detection in an asymptomatic population: fecal immunochemical test for hemoglobin vs. fecal M2-type pyruvate kinase     

Gian Paolo Caviglia  Luca Cabianca  Sharmila Fagoonee  Fabrizio M. Gili 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2016,26(1):114-120

Introduction

Screening programs for colorectal cancer (CRC) are mainly based on a first-line fecal immunochemical test for hemoglobin (FIT). Fecal M2-type pyruvate kinase (M2-PK) has been evaluated in clinical settings showing promising results for early CRC detection. However, the impact of fecal M2-PK assessment on the performance of first-round CRC screening programs is not known. We investigated whether fecal M2-PK alone or in combination with FIT may improve CRC screening efficacy in the general population.

Materials and methods

A total of 1027 asymptomatic subjects (median age 66 [59-74] years; females 504 [49.1%]), identified through the general practitioners’ rosters, were invited for the collection of 2 fecal samples for FIT and M2-PK evaluation. Participants with at least positive one fecal test were referred for colonoscopy. Quality indicators for screening performance were calculated and analyzed using Fisher’s exact test.

Results

Overall, 572 subjects underwent both FIT and M2-PK assessment (participation rate 55.7%): 93 participants showed positive results for at least one test (positivity rate 16.3%). Only 10 patients were positive for both tests. Attendance rate to colonoscopy was 86.0% and a total of 65 adenomas and 7 cancers were detected. Combined use of FIT and fecal M2-PK permitted the identification of 18 more neoplasm (25%) without improving colonoscopy workload, as deduced by the comparable number needed to scope (P = 0.402).

Conclusion

The addition of M2-PK testing to FIT offers the potential to detect additional neoplasms that either do not bleed or only bleed intermittently without reducing participation rate and without increasing endoscopy workload.Key words: biomarker, colorectal cancer, occult blood, M2-type pyruvate kinase, screening  相似文献   

Brazil: Ministry of Education Initiatives for HIV/AIDS Prevention and Control     

Souza  Paolo Renato 《Prospects》2002,32(2):181-186

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Undesirable economic growth via agents’ self-protection against environmental degradation     

Angelo Antoci  Paolo Russu 《Journal of The Franklin Institute》2007,344(5):377-390

Our model analyzes the effects of the interplay between environmental degradation and consumption choices on economic growth dynamics and on economic agents’ welfare. We show that if private goods can be consumed as substitutes for environmental goods, then economic growth may be fueled by environmental deterioration. In this context, undesirable economic growth may occur, characterized by an inverse correlation between aggregate capital accumulation and economic agents’ welfare.  相似文献   

Hypercomputation and the Physical Church-Turing Thesis   总被引：1，自引：0，他引：1  

Cotogno  Paolo 《The British journal for the philosophy of science》2003,54(2):181-223

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Integrated reflectography and thermography for wooden paintings diagnostics     

Dario Ambrosini  Claudia Daffara  Roberta Di Biase  Domenica Paoletti  Luca Pezzati  Roberto Bellucci  Francesca Bettini 《Journal of Cultural Heritage》2010,11(2):196-204

The need of inspecting a masterpiece of fine art without affecting it led to develop non destructive methods of investigation. In the field of art conservation, several diagnostic techniques are being widely used to inspect works of art, giving different but complementary results. The present work deals with two of these methods, reflectography and thermography, both techniques examining objects in the infrared spectrum but in different wavelength bands. Their integrated data potentially provide a powerful tool for mapping hidden features and alterations of artworks. This was confirmed during the inspections of a 13th century panel painting under restoration at the Opificio delle Pietre Dure laboratories (Florence, Italy). A graphical user interface was also designed to aid operators in the field of conservation dealing with the results of the two IR methods. Many options such as image adjustment, comparison, overlaying and transparency variation, in addition to thermographic elaborations, have been made available to users. Imaging data integration provides a multi-layered and multi-spectral representation of the painting that yields a comprehensive diagnosis confirms the anomalies individuation and reduces the ambiguities of information coming from a single diagnostic method.  相似文献   

Assessment of thermo-hygrometric quality in museums: Method and in-field application to the “Duccio di Buoninsegna” exhibition at Santa Maria della Scala (Siena,Italy)     

Stefano Paolo Corgnati  Marco Filippi 《Journal of Cultural Heritage》2010,11(3):345-349

Maintaining the microclimatic parameters at the desired value is essential for artefacts preservation. In order to control the status of the microclimatic parameters, a continuous monitoring of the indoor environmental provides conservators, curators, restorers, and lenders with an exact knowledge of the microclimatic conditions under which the works of art are kept. Moreover, the monitoring results give important information in order to make adequate changes to the control strategy of microclimatic parameters. From this point of view, monitoring is an essential tool to develop an actual preventive control programme aimed at maintaining the optimal microclimatic conditions for preservation. As a consequence, long-term monitoring has to be applied to prevent deterioration of works of art. The widespread opinion that a correct approach to the topic of microclimate control for artefacts preservation is not only and necessarily to provide buildings with sophisticated environmental control systems, but mainly to investigate the actual environmental dynamics and, before any structural intervention, to define the compatibility between the climate control potentials and the preservation requirements, has become more and more firm among the experts. Monitoring also allows to verify the capacity of the “building and Heating, Ventilation and Air Conditioning (HVAC)” system to maintain the desired thermo-hygrometric values within the operating conditions. To this aim, the Italian Standard UNI 10829 (1999) defining monitoring, elaboration and analysis of the microclimatic data as supporting actions for artefacts preservation, led to the need of a long-term monitoring and of a statistical approach to the data management. The approach proposed by the Italian Standard has been recently adopted by a European Standard (EN 15251, 2007). In accordance with the Standards mentioned above, in this paper an operational procedure to assess the thermo-hygrometric quality in museums is firstly synthetically presented and than applied to a case study. In particular, the procedure is developed in order to define the thermo-hygrometric quality level of the exhibition areas in the large museum complex of “Santa Maria della Scala” in Siena (Italy) during the international temporary exhibition “Duccio. La nascita della pittura senese” (“Duccio. The birth of Sienese Painting”).  相似文献   

Optimal sampling frequency in recording of resistance training exercises     

Paolo Bardella  Irene Carrasquilla García  Marco Pozzo  Julio Tous-Fajardo  Eduardo Saez de Villareal 《Sports biomechanics / International Society of Biomechanics in Sports》2017,16(1):102-114

The purpose of this study was to analyse the raw lifting speed collected during four different resistance training exercises to assess the optimal sampling frequency. Eight physically active participants performed sets of Squat Jumps, Countermovement Jumps, Squats and Bench Presses at a maximal lifting speed. A linear encoder was used to measure the instantaneous speed at a 200 Hz sampling rate. Subsequently, the power spectrum of the signal was computed by evaluating its Discrete Fourier Transform. The sampling frequency needed to reconstruct the signals with an error of less than 0.1% was f_99.9 = 11.615 ± 2.680 Hz for the exercise exhibiting the largest bandwidth, with the absolute highest individual value being 17.467 Hz. There was no difference between sets in any of the exercises. Using the closest integer sampling frequency value (25 Hz) yielded a reconstruction of the signal up to 99.975 ± 0.025% of its total in the worst case. In conclusion, a sampling rate of 25 Hz or above is more than adequate to record raw speed data and compute power during resistance training exercises, even under the most extreme circumstances during explosive exercises. Higher sampling frequencies provide no increase in the recording precision and may instead have adverse effects on the overall data quality.  相似文献