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Shibba Takkar Chhabra Shivani Mehta Sandeep Chhabra Manikant Singla Naved Aslam Bishav Mohan Gurpreet Singh Wander 《Indian journal of clinical biochemistry : IJCB》2018,33(2):235-238
Torsades de pointes with prolonged QTc interval is a form of ventricular tachycardia. Many predisposing factors have been identified and hypocalcemia is among the rare ones. Our case illustrates that though rare, hypocalcemia might manifest as torsades de pointes with prolongation of QTc interval. Early diagnosis and management of dyselectrolytemia can prevent these patients from catastrophic torsades de pointes. 相似文献
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Kalpana Luthra Suman Vasisht Shivani Chhabra K. R. Raju D. P. Agarwal S. C. Manchanda L. M. Srivastava 《Indian journal of clinical biochemistry : IJCB》1998,13(1):12-19
Lipoprotein Lp(a) excess has been identified as a powerful predictor of premature atherosclerotic vascular diseases. To evaluate
this in a North-Indian population, 130 CAD patients and 130 controls were analyzed. The size of the apo(a) phenotypic isoforms
was inversely proportional to Lp(a) concentrations. The mean concentration of Lp(a) in the CAD patients was 42±34 mg/dl whereas
in the normal subjects it was much lower, 27±27 mg/dl. 157 subjects out of the total 260 subjects showed plasma levels of
>20mg/dl. The frequency of high Lp(a) levels was much higher in patients(73%) than controls (43%). These data suggest (1)
that there is heterogeneity of the Lp(a) polymorphism, (2) Higher Lp(a) levels were found in patients than in the controls,
(3) Patients showed 1.5 fold increase in Lp(a) levels as compared to the controls. We conclude that low molecular weight apo(a)
isoforms are significantly associated with increased risk of CAD in the North-Indian population. 相似文献
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Narotam Sharma Veena Sharma Tariq Masood Satish Chandra Nautiyal Shivani Sailwal Rajesh K. Singh Rajeev K. Kushwaha R. K. Singh 《Indian journal of clinical biochemistry : IJCB》2013,28(2):189-192
Ankylosing spondylitis is a chronic inflammatory disease that has been linked to the human leukocyte antigen class I allele HLA-B27. More than 90 % of patients with ankylosing spondylitis possess the HLA-B27 allele, but only 1 % of people with HLA-B27 develop the disease. Ankylosing spondylitis predominately affects young males. The present study was planned to find out the involvement of HLA-B27 specific allele in relation to age and sex in symptomatic suspected patients of ankylosing spondylitis using conventional PCR technology. Forty symptomatic patients of ankylosing spondylitis were included in the present study. SSP–PCR technique was used to detect the HLA-B27 specific allele. This study showed (out of 40 symptomatic suspected cases of ankylosing spondylitis only 12 patients were detected positive with HLA-B27 allele, while remaining 28 were negative) that the positivity rate for ankylosing spondylitis with HLA-B27 allele is low. Furthermore, it was observed that the males above 50 years are more prone to develop AS with HLA-B27 specific allele. It could be concluded that the conventional PCR technology is a rapid, sensitive, and confirmatory method for the diagnosis of ankylosing spondylitis. 相似文献
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A. P. S. Narang H. S. Bains Shivani Kansal D. Singh 《Indian journal of clinical biochemistry : IJCB》2006,21(1):89-94
Human milk samples were collected from 86 mothers induced in the study on days 3, 7, 14 and 28 of lactation. The mothers were
divided into three groups on the basis of gestation viz. group 1: 37–41 weeks (n=41), group II: 33–36 (n=23) and group III:
<33 weeks gestation (n=22). All the samples were analysed for the estimation of fat, lactose and protein. The results obtained
from the investigations were statistically analysed. The analysis of the results revealed a lower amount of fat and lactose
in preterm milk as compared to term milk (p<0.01). These were found to increase in amount with increasing postnatal age (p<0.05).
The protein levels were observed to be significantly higher in preterm than term milk (p<0.01). These were observed to decrease
significantly with increase in postnatal age (p<0.01). 相似文献
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Pratima Tripathi M. K. Misra Shivani Pandey 《Indian journal of clinical biochemistry : IJCB》2012,27(3):296-299
Oxidative stress conditions associated with atherosclerosis leads to oxidative modification of low-density lipoprotein (LDL). The body’s capabilities to inhibit LDL oxidation and to remove or neutralize the atherogenic oxidized LDL (ox-LDL) are limited. When the LDL cholesterol level increases in the blood, it leads to dangerous consequences like atherosclerosis, leading to myocardial infarction. The major effect of an antioxidant in the LDL environment is to prevent the formation of ox-LDL (during atherogenesis. Strategies to reduce LDL oxidation and prevent atherogenesis can involve the enrichment of arterial cells with potent antioxidants that can prevent oxidative damage to the arterial wall. The objective of this study is to evaluate the effect of l-arginine on serum lipid and cholesterol levels in the patients of acute myocardial infarction (AMI). The study consisted of 70 AMI patients and 60 healthy individuals (serving as control) age 55–65 years. Serum levels of total cholesterol, high density lipoprotein (HDL), LDL and Triglycerides were determined on day 1 and day 15 of l-arginine administration (oral dose 3 g/day). The total cholesterol/HDL and the LDL/HDL ratio were calculated and compared. As per the observations, l-arginine administration was found to improve the lipid profile of the subjects. Hence it could be used as an adjuvant therapy for AMI and as a preventive measure for the onset of the disease in the healthy elderly also. 相似文献
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In this article, we describe our experiences of conducting a series of workshops titled ‘It’s a MATERIALS world!’ to popularize Materials Science among school children in India. Some of the hands-on activities that can be performed with easily available ingredients/equipment in a classroom are described for the benefit of educators. 相似文献
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Narotam Sharma Veena Sharma Prem Raj Singh Shivani Sailwal Rajeev S. Kushwaha Rajesh K. Singh Satish C. Nautiyal Pankaj Mishra Tariq Masood R. K. Singh 《Indian journal of clinical biochemistry : IJCB》2013,28(3):305-308
Genitourinary tuberculosis is a disease of the genitourinary system which includes the entire urinary tract and reproductive system. Genital tuberculosis is an important cause of female infertility, especially in developing nations like India. In the present study, a total of 257 clinical specimens comprising of endometrial biopsy (109), endometrial curetting (42), menstrual blood (8), semen (17), placenta (11) and urine (70) were collected from patients and subjected for PCR, Culture and AFB detection. The endometrial biopsy, endometrial curetting, menstrual blood, semen, placenta, urine showed 30.2, 45.2,12.5, 5.8, 27.2, 31.4 %, positivity rate for tuberculosis by PCR, 7.3, 9.5, 25.0, 0, 9, 8.5 % by culture and 1.8, 2.3, 0, 0, 0, 2.8 % respectively by AFB smear. Being a novel, rapid technique, PCR is the method of choice for rapid diagnosis and management of genitourinary tuberculosis shared with the other concerned tests. This study reveals that genital tuberculosis can occur in any age group, however, the majority of patients were from reproductive age (nearly 75 % of them were from 20–45 years of age) group. 相似文献
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Malhotra Shivani Kumar Amit Dutta Rubina 《Education and Information Technologies》2021,26(3):2607-2621
Education and Information Technologies - As a technology the effect of the Internet of Things (IoT) is so strong that it has changed the way of living. The transition is also apparent in the field... 相似文献
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The use of personal response devices (or “clickers”) in the classroom has increased in recent years. While few quantitative
studies on the effectiveness of clickers have been published, it is generally reported that clickers have been well-received
by the students who use them. Two separate populations (Winter 2006 and Spring 2006) of engineering students were given clickers
to use during a general chemistry class. Clicker use was compared to student grades for each course. During both terms, a
higher percentage of female students than male students “actively participated” in the lectures, where active participation
was defined as answering more than 75% of the clicker questions over the course of the term. Active male students earned final
grades about 10 points higher than non-active male students. Active female students, however, scored only about 5 points higher
than non-active female students. Student learning was assessed by comparing performance on exam questions and clicker questions
with similar content. Students who answered clicker questions correctly were 11–13% more likely to answer the corresponding
exam questions correctly than were students who did not answer the clicker question. In this paper, we demonstrate the effectiveness
of clicker use in the classroom and examine gender differences associated with this use. 相似文献
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