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D. Suhasini 《Indian journal of clinical biochemistry : IJCB》2000,15(2):128-133
We performed a pilot accuracy study on glucometers from three sources: “Advantage” from Boehringer Mannheim (A), “Glucometer* 4” from Bayer (B) and “One Touch Basic” from Life Scan (C) and compared these results with the results on autoanalyzers-Dimension
RxL (1) and Hitachi 704 (2). Each glucometer was tested with venous blood in duplicate, from three different groups of 20
patients each, at random, on three different days, in our outpatient phlebotomy section. The rest of the sample was collected
into heparinized tubes & the plasma separated within 15 minutes of sample collection & analyzed on both the analyzers in duplicates.
The data were analyzed for accuracy by tabulating the number and percentage of test values that vary from the analyzer (reference)
method by 10% or less, by 10% to 20%, or greater than 20% and the results tabulated on the Accuracy Study Table. This being
a pilot study and the numbers being small, it may be suggested from the Accuracy Study Table alone, that the results of glucose
in whole blood done with glucometer (A) were comparable with that of plasma values without applying any factor; whereas the
results with glucometers (B) & (C) need to be divided by 1.11 to be comparable with plasma results; statistically though,
results with glucometer (C) were comparable with or without factor. Patients using glucometers need to be alerted about the
variance in their glucose results when compared to laboratory results, more clearly by the respective companies in their product
inserts. An external quality control material that is glucometer method specific is needed, so that the Clinical Biochemistry
laboratory in any hospital setup can more effectively monitor the performance of the glucometers in the wards periodically. 相似文献
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Shrilekha Sairam Suhasini Domalapalli Sundaram Muthu Jayanthi Swaminathan Vivek A. Ramesh Lalitha Sekhar Palak Pandeya Udhaya Balasubramaniam 《Indian journal of clinical biochemistry : IJCB》2014,29(3):290-297
Clinical reference intervals among Indian population are poorly defined. Therefore, there is an urgent need to establish local clinical laboratory reference intervals for healthy Indian population. The present study aimed to identify the 95 % reference interval for hematological and biochemical parameters in apparently healthy Indian population. We undertook a multicentric cross-sectional study conducted at Apollo Hospitals Educational and Research Foundation across India. Of which 10,665 reference individuals identified as healthy by physicians. The 95 % of the reference distribution was estimated using 2.5th and 97.5th percentile reference limits. The 95 % reference intervals for hemoglobin (Males: 12.3–17 g/dL; Females: 9.9–14.3 g/dL), platelet count (Males: 1.3–3.8; Females: 1.3–4.2 Lakhs/µL), erythrocyte sedimentation rate (Males: 2–22; Females: 4–55 mm/h), serum uric acid in males: 3.5–8.2 mg/dL, gamma glutamyl transferase (Males: 13–61 U/L), fasting blood glucose (Males: 78–110 mg/dL), total cholesterol (Males: 115–254 mg/dL), low density lipoprotein (Males: 60–176 mg/dL) and triglycerides (Males: 55–267 mg/dL, Females: 52–207 mg/dL) were different from currently used reference values. Additionally need for gender based partitioning were observed for triglycerides and gamma glutamyl transferase. The observed findings are of clinical significance and it needs to be validated with additional community based studies. 相似文献
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