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Dietary fiber components e.g. cellulose, hemicellulose and lignin are estimated in 53 commonly consumed Indian foods, with an objective to get an estimate of habitual level of intakes in Indians. Results indicate that there is a wide range of variation in Indian foods in cellulose, hemicellulose and lignin content for all the classes of Indian foods. This is useful to modify the diets with varying proportions of fiber but giving the same level of calories. When our values were compared with fifteen values obtained by Kamat and Belavady (1) and nine values of Anuradhaet al (7) the values were found to be comparable (P>.01). However they were significantly different (P<.01) when compared with eleven values of Premakumari (8). A computer program FIBER. INT based on cooked factors is developed for the calculation of habitual level of cellulose, hemicellulose and lignin for Indian diets. Total NDF is in the range 20.5–47.6 grams per day for 28 adult males and 15.2–26.1 grams per day for 6 females. However fiber expressed as gram per 1000 calories is 13.1 in females as compared to 11.9 in males. Diets with combination of wheat and sorghum were highest in fiber content (12.5 gram per 1000 K calories).  相似文献   
2.
HIV-infected adults may be likely to have metabolic syndrome (MS) at younger ages and in the absence of obesity compared with general population. In the present study, we determined prevalence of MS and its association with oxidative deoxy nucleic acid (DNA) damage in HIV-1 infected patients with different ART status. We used plasma level of the oxidized base, 8-hydroxy-2-deoxyguanosine (8-OHdG), as a biomarker of oxidative DNA damage. To measure plasma 8-OHdG we used 8-OHdG enzyme-linked, immunosorbent assay. The biomarkers of MS were insulin resistance, Cholesterol/HDL ratio, Waist circumference and Hypertension. MS and oxidative DNA damage were significantly higher in HIV-positive patients with second line ART and first line ART than ART-naive patients. In a logistic regression analysis, increased MS was positively associated with the increased DNA damage (OR: 29.68, 95%:13.47, CI: 65.40) P = 0.0001. ART plays a significant role in the development of MS and oxidative DNA damage in HIV-positive patients taking antiretroviral therapy. Awareness and knowledge of MS and DNA damage in HIV/AIDS patients may prove helpful to clinicians to manage non-AIDS diseases such as cardiovascular disease and cancer. To determine exact role of ART in induction of MS and DNA damage larger studies are warranted.  相似文献   
3.
The aim of this study was to monitor serum nitric oxide levels at various times, intraoperatively and following liver transplantation in humans. Nitric oxide production was assessed by cadmium reduction method in 15 patients undergoing liver transplantation. We observed strong correlation between nitric oxide production and allograft rejection. Sustained rise in nitric oxide level after transplantation might provide an indication of acute allograft rejection. Therefore measurement of nitric oxide, a stable end product appears to be an excellent marker that can help in the development of strategies intended to improve graft viability and patient’s survival.  相似文献   
4.
Liver transplantation is an accepted therapy for chronic liver disease patients. These patients generally have low levels of fat soluble vitamins, which have important antioxidant roles. Therefore, this study was undertaken to investigate whether such patients had evidence of antioxidant depletion and increased lipid peroxidation before transplant and whether the subsequent ischemia and reperfusion encountered during liver transplantation have any effect on antioxidant levels and lipid peroxidation. We assessed plasma total antioxidant capacity and serum lipid peroxide in 12 patients undergoing liver transplantation and equal numbers of healthy subjects. We found that before reperfusion, antioxidant levels were significantly decreased along with significantly elevated lipid peroxidation levels as compared with healthy controls (P<0.001). On reperfusion of the liver graft, further declined values of total antioxidant accompanied with highly elevated lipid peroxidation were seen than those of pre-reperfusion samples (P<0.001). This data shows that patients undergoing liver transplant have lowered antioxidant defenses and evidence of free radical damage, which compound the additional insult of reperfusion injury. Therefore antioxidant therapy in these patients before transplantation may ameliorate the effects of reperfusion.  相似文献   
5.
Dietary fiber alone or coupled with other factors affects the utilization of nutrients. In the present investigation, response of 4 men consuming diets at 3 levels of energy and neutral detergent fiber (NDF) was studied. Pooled ANOVA for 3 experiments with 4 subjects showed significant differences between the experiments within the subject (P< .01) for digestibility of fat, carbohydrate, nitrogen and NDF. Results indicate that habitual NDF intakes of about 40 grams per day have digestibility of 49% and that amount and source of fiber modify the fat digestibility.  相似文献   
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