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B. Venkata Raman D. N. Rao T. M. Radhakrishnan 《Indian journal of clinical biochemistry : IJCB》2004,19(1):105-109
Enteromorpha compressa a marine green algal species grows extensively in North coastal Andhra Pradesh. Besides its nutritional importance it has
also been identified as source of anti-anaphylactic compound(s).E. compressa extracts alleviated the IgE levels raised against ovalbumin and other allergens in mice. Further,Enteromorpha extract also significantly down regulated the serum IgE levels in different murine models irrespective of their genetic background.
The results obtained in this study suggest thatE. compressa extract has compound(s), which inhibit IgE immune response and may have potential in curing various types of allergies. 相似文献
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P-selectin, a cell adhesion molecule is elevated in many inflammatory conditions including preeclampsia which is characterized
by generalized endothelial dysfunction and vasoconstriction presumably due to free radicals or mediators released by defective
placentation. Vitamin E has been documented to protect cell membranes from oxidative damage and also decrease platelet aggregation.
The role of vitamin E in pre-eclampsia is contradictory and hence the study was undertaken. Soluble P-selectin was measured
by ELISA and Vitamin-E levels in plasma was estimated spectrofluorometrically. In our study the effect of supplementation
of 400 IU/day of Vitamin E (a-tocopheryl acetate) to patients of pre-eclampsia showed significant decreased levels of soluble
P-selectin by 2nd week as compared to patients given placebo (P = 0.005). In this short period of study no direct correlations were observed between Vitamin E or P-selectin levels with
blood pressure as well as with proteinuria. Future studies may focus on the effect of a-tocopheryl acetate or the phosphate
form of Vitamin-E, recently proposed to be the more active form on other inflammatory markers like IL-6, an important stimuli
of P-selectin release in pre-eclampsia. 相似文献
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The dropout rate among Spanish university students is very high compared to the European mean, creating a pressing need for the introduction of policies and programmes aimed at increasing rates of persistence. In this article, we study this problem by combining students’ perceived learning outcomes with their dropout intentions, and we propose a research model that considers subjective factors that might impact this decision. The model is estimated for two degree courses: Business Administration and Nursing. The estimation method uses structural equations based on the partial least squares algorithm. This allows the construction of indices for the variables of interest, enabling us to make comparisons between courses and over time. To reduce dropout intentions, efforts need to be focused on obtaining better cognitive outcomes, as well as on achieving a higher level of student satisfaction with their university experience. 相似文献
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State-of-the-art of modeling complex information systems is briefly discussed. A distinction is made between macrolevel and microlevel modeling of such systems. Modeling approaches and techniques, appropriate for each of these two levels are described and assessed. 相似文献
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P. Vasanth Raj K. Nitesh Jain Prateek M. Neena Sankhe J. Venkata Rao C. Mallikarjuna Rao N. Udupa 《Indian journal of clinical biochemistry : IJCB》2011,26(4):378-384
Twenty four Wistar strain albino rats were used for the investigations. Lecithin 50 and 100 mg/kg b wt was administered for
1 week by oral route. Liver damage was induced by intra peritoneal administration of 400 mg/kg b wt d-galactosamine on the last day. At the end of the study animals were sacrificed and liver enzyme levels, histopathology, mitochondrial
integrity, expression of p53, Bax and Bcl-2 mRNA levels were studied. Increases in the liver enzyme levels by d-GalN were significantly inhibited by pretreatment with lecithin. Histopathological observation further confirmed the hepatoprotective
effect of lecithin. In addition, the disruption of mitochondrial membrane, up regulation of Bax and down regulation of Bcl-2
mRNA levels in the liver of d-GalN intoxicated rats were effectively prevented by pretreatment with lecithin. The results of the present study validate
our conviction that d-GalN causes hepatic damage via mitochondrial pathway involving Bax and Bcl-2. 相似文献
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