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Efthimiadou A Asimakopoulos B Nikolettos N Giatromanolaki A Sivridis E Lialiaris TS Papachristou DN Kontoleon E 《Journal of sports sciences》2006,24(8):849-854
Although angiogenetic therapy using recombinant growth factors holds much hope for the treatment of ischaemic diseases, there are still many unanswered questions, including the method of administration, the correct dose of these factors, and the duration of the therapeutic approach. Exercise has also been suggested to induce neovascularizaiton in muscles. We evaluated the angiogenetic effects of the intramuscular administration of basic-fibroblast growth factor (b-FGF) and acidic-fibroblast growth factor (a-FGF) in rat heart, compared with rats who exercised daily. In conclusion, both the intramuscular administration of b-FGF and exercise increased significantly angiogenesis in the heart in contrast to the intramuscular administration of a-FGF, which was ineffective. 相似文献
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Anna Efthimiadou Byron Asimakopoulos Nikos Nikolettos Alexandra Giatromanolaki Efthimios Sivridis Theodoros S. Lialiaris 《Journal of sports sciences》2013,31(8):849-854
Abstract Although angiogenetic therapy using recombinant growth factors holds much hope for the treatment of ischaemic diseases, there are still many unanswered questions, including the method of administration, the correct dose of these factors, and the duration of the therapeutic approach. Exercise has also been suggested to induce neovascularizaiton in muscles. We evaluated the angiogenetic effects of the intramuscular administration of basic-fibroblast growth factor (b-FGF) and acidic-fibroblast growth factor (a-FGF) in rat heart, compared with rats who exercised daily. In conclusion, both the intramuscular administration of b-FGF and exercise increased significantly angiogenesis in the heart in contrast to the intramuscular administration of a-FGF, which was ineffective. 相似文献
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Efthimios Tambouris Maria Zotou Konstantinos Tarabanis 《Education and Information Technologies》2014,19(1):61-86
Traditional education seems to gradually and moderately make way for self-directed and student-centred learning strategies that will efficiently enable students to reach their full potentials and will sufficiently prepare them for their upcoming professional careers. Problem-Based Learning (PBL) is such a strategy, since it enables active participation by shifting the focus from the delivery of knowledge to its creation by the students, in their endeavour to implement problem-based projects. PBL is more commonly used in project-oriented courses, where students have to not only build but also apply new knowledge in real world contexts and therefore familiarize themselves with work conditions. Online technologies, such as cognitive tools, are able to harmonize this shift by visualizing some of the more demanding steps of PBL as well as facilitating collaboration and knowledge building. The aim of this paper is to investigate the incorporation of cognitive technologies in project-oriented courses, using a Blended PBL strategy. To this end, we implement our findings in a Project Management postgraduate course. Based on the gathered results, we propose a framework that can guide the design of project-oriented courses and we argue that its adaptation can exploit the identified strengths and avoid the weaknesses and lead to successful and immersive learning processes. 相似文献
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Zotou Maria Tambouris Efthimios Tarabanis Konstantinos 《Educational technology research and development : ETR & D》2020,68(6):3393-3424
Educational technology research and development - Problem based learning (PBL) supports the development of transversal skills and could underpin the training of a workforce competent to withstand... 相似文献
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Efthimios Trevlas Vasilios Grammatikopoulos Nikolaos Tsigilis Evridiki Zachopoulou 《Early Childhood Education Journal》2003,31(1):33-39
This study was designed to examine the underlying structure of the Children's Playfulness Scale (CPS). The CPS was administered to 602 children who were randomly divided into two groups (calibration and validation group). The calibration group (n= 279) included 137 boys and 142 girls, and the validation group (n= 323) included 162 boys and 161 girls, ranging in age from 4 to 6 years. A one-factor model was postulated and supported. According to the model, 5 variables measuring children's playfulness loaded on one factor (playfulness). In addition, the proposed model was found to be invariant across the two groups. Good cross-generalizability of the CPS appears to support its validity. Educators working in a preschool/kindergarten setting may use it with confidence when evaluating children's playfulness. 相似文献
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