Plasma irisin is increased following 12 weeks of Nordic walking and associates with glucose homoeostasis in overweight/obese men with impaired glucose regulation     

Ayhan Korkmaz  Mika Venojärvi  Niko Wasenius  Sirpa Manderoos  Keith C. Deruisseau  Eva-Karin Gidlund 《European Journal of Sport Science》2019,19(2):258-266

Irisin is a myokine that is thought to be secreted in response to exercise that may help to prevent obesity and maintain normal glucose metabolism. In this study we investigated the associations between irisin and glucose homeostasis in middle-aged, overweight and obese men (n?= 144) with impaired glucose regulation, and the impact of exercise training on these relationships. The participants underwent 12 weeks of resistance or aerobic (Nordic walking) exercise training three times per week, 60 minutes per session. Venous blood (n?=?105) and skeletal muscle samples (n?=?45) were obtained at baseline and post-intervention. Compared to controls, Nordic walking, but not resistance training, increased irisin levels in plasma (9.6?±?4.2%, P?=?0.014; 8.7?± 4.9%, P?=?0.087; respectively) compared to controls. When considering all subjects, baseline irisin correlated positively with atherogenic index of plasma (r?=?0.244, P?=?0.013) and 2-hour insulin levels (r?=?0.214, P?=?0.028), and negatively with age (r?=??0.262, P?=?0.007), adiponectin (r?=??0.240, P?=?0.014) and McAuley index (r?=??0.259, P?=?0.008). Training-induced FNDC5 mRNA changes were negatively correlated with HbA1c (r?=??0.527, P?=?0.030) in the resistance training group and with chemerin in the Nordic walking group (r?=??0.615, P?=?0.033). In conclusion, 12-weeks of Nordic walking was more effective than resistance training in elevating plasma irisin, in middle-aged men with impaired glucose tolerance. Thus, the change in irisin in response to exercise training varied by the type of exercise but showed limited association with improvements in glucose homeostasis.  相似文献   

Why teachers find it difficult to include students with EBD in mainstream classes     

Ulrika Gidlund 《International Journal of Inclusive Education》2018,22(4):441-455

In Sweden, teachers in mainstream schools show frustration and insecurity about how to organise education for inclusion and diversity. This article contributes to the understanding of how they articulate their view of the advantages and disadvantages of including students with EBD in mainstream classes. To study teachers’ understanding, an approach of discourse theory which takes inspiration from Laclau and Mouffe (1985. Hegemony and Socialist Strategy. London: Verso) was applied. The empirical material consisted of 6 focus group interviews and 37 individual interviews based on stimulus texts. According to the results, the prevailing discourses focused on the disadvantages of it. However, they were articulated differently and filled with meaning mainly by three recurring nodal points: (1) problems, (2) dilemmas and (3) impossibility. The advantages of including students with EBD in mainstream classes were only to be found in the antagonistic discourses. They were articulated in different ways but were overpowered by others and therefore failed to fix the meaning. The overall conclusion is that teachers base their understanding on both their experiences and on the policy of the Educational Act, but the pragmatic discourse of the disadvantages was hegemonic to the ideological antagonistic discourse of the advantages.  相似文献