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Due to endurance exercise-induced increases of the cardiac biomarkers troponin and B-type natriuretic peptide (BNP), which are usually elevated in patients with acute myocardial infarction and heart failure and used in clinical practice as diagnostic tools in these diseases, the clinical and sportsmedical relevance of these exercise-induced increases was unclear. Therefore, the aim was to examine this topic systematically by consecutive studies. Considering the acute effects of endurance exercise, an intensity- and duration-dependent short-term elevation could be demonstrated in the majority of healthy athletes without pathological relevance. Considering the chronic effects of endurance exercise it could be shown that regular and competitive endurance exercise training induces an athlete??s heart with harmonic eccentric hypertrophy of the left and right ventricle, which also is not of pathological relevance. In conclusion it can be assumed from the results of these studies that acute and chronic endurance exercise is not harmful for the healthy heart.  相似文献   
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