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PurposeThis review aimed to synthesize previous findings on the test–retest reliability of the 30–15 Intermittent Fitness Test (IFT).MethodsThe literature searches were performed in 8 databases. Studies that examined the test–retest reliability of the 30–15 IFT and presented the intraclass correlation coefficient (ICC) and/or the coefficient of variation (CV) for maximal velocity and/or peak heart rate were included. The consensus-based standards for the selection of health measurement instruments (COSMIN) checklist was used for the assessment of the methodological quality of the included studies.ResultsSeven studies, with a total of 10 study groups, explored reliability of maximal velocity assessed by the 30–15 IFT. ICCs ranged from 0.80 to 0.99, where 70% of ICCs were ≥0.90. CVs for maximal velocity ranged from 1.5% to 6.0%. Six studies, with a total of 7 study groups, explored reliability of peak heart rate as assessed by the 30–15 IFT. ICCs ranged from 0.90 to 0.97 (i.e., all ICCs were ≥0.90). CVs ranged from 0.6% to 4.8%. All included studies were of excellent methodological quality.ConclusionFrom the results of this systematic review, it can be concluded that the 30–15 IFT has excellent test–retest reliability for both maximal velocity and peak heart rate. The test may, therefore, be used as a reliable measure of fitness in research and sports practice. 相似文献
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Unic A Derek L Hodak N Marijancevic D Ceprnja M Serdar T Krhac M Romic Z 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2011,21(3):231-242
Endothelins (ET) are a group of endogenous peptides, which have a strong and long-lasting vasoconstrictive effect. Three isoforms of endothelins coded by three different genes have been identified to date. Endothelin-1 (ET-1) is the most potent vasoconstrictive agent currently identified, and it was originally isolated and characterized from the culture media of aortic endothelial cells. Two other isoforms, named endothelin-2 (ET-2) and endothelin-3 (ET-3), were subsequently identified, along with structural homologues isolated from the venom ofActractapis engaddensis known as the sarafotoxins. The biological effects of endothelin production are determined via activation of one or two G-protein coupled receptors, endothelin receptors A (ETRA) and B (ETRB1 and ETRB2). Recently endothelin receptor C (ETRC) was discovered, however, its functions and distribution still remain unclear. The effects mediated by ET-1 via ETRA are vasoconstriction, bronchoconstriction and secretion of aldosterone. Agonists related to the ETRB1 activation cause vasodilatation by stimulating NO, PGI2 and endothelium-derived hyperpolarizing factor (EDHF). In contrast, coupling to ETRB2 causes vasoconstriction. Involvement of ET has been demonstrated in the pathophysiology of certain disorders. In this review, we discuss the physiological and pathophysiological role of endothelium-derived ET-1, the pharmacology of its two receptors, focusing on the role of ET-1 in the development of some pathophysiological conditions. 相似文献
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Cubranic Z Madzar Z Matijevic S Dvornik S Fisic E Tomulic V Kunisek J Laskarin G Kardum I Zaputovic L 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(2):225-236
Introduction:
This study aimed to assess whether heart fatty acid-binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) could be used for the accurate diagnosis of acute myocardial infarction (AMI) in acute coronary syndrome (ACS) patients.Materials and methods:
The study included 108 ACS patients admitted to a coronary unit within 3 h after chest pain onset. AMI was distinguished from unstable angina (UA) using a classical cardiac troponin I (cTnI) assay. H-FABP and GPBB were measured by ELISA on admission (0 h) and at 3, 6, 12, and 24 h after admission; their accuracy to diagnose AMI was assessed using statistical methods.Results:
From 92 patients with ACS; 71 had AMI. H-FABP and GPBB had higher peak value after 3 h from admission than cTnI (P = 0.001). Both markers normalized at 24 h. The area under the receiver operating characteristic curves was significantly greater for both markers in AMI patients than in UA patients at all time points tested, including admission (P < 0.001). At admission, the H-FABP (37%) and GPBB (40%) sensitivities were relatively low. They increased at 3 and 6 h after admission for both markers and decreased again after 24 h. It was 40% for H-FABP and approximately 2-times lower for GPBB (P < 0.01). In AMI patients, both biomarkers had similar specificities, positive- and negative-predictive values, positive and negative likelihood ratios, and risk ratios for AIM.Conclusion:
H-FABP and GPBB can contribute to early AMI diagnosis and can distinguish AMI from UA. 相似文献4.
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