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What does it take to change a school’s mathematics achievement profile from low to one that is proficient and advanced? Is this transformed achievement profile sustainable? Such is the story presented here, in this three-phase case study of a K-8 urban charter school’s mathematics program. The first phase discusses the school’s mathematics program as it existed in 2006. The second phase discusses the contents and interventions implemented which transformed the student achievement scores over a period of 3 years (2006–2009) from low achieving to proficient and advanced. The third phase is a follow-up mixed-methods investigation that was conducted to determine whether the achievement was sustainable and how the program changed. The interventions designed and implemented over the initial 3-year period are discussed, as are the findings of the follow-up study. This is discussed with reference to impacting change in student achievement and its relative significance for future work.  相似文献   
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Exosomes, nanosized membrane-bound vesicles released by cells, play roles in cell signaling, immunology, virology, and oncology. Their study, however, has been hampered by difficulty in isolation and quantification due to their size and the complexity of biological samples. Conventional approaches to improved isolation require specialized equipment and extensive sample preparation time. Therefore, isolation and detection methods of exosomes will benefit biological and clinical studies. Here, we report a microfluidic platform for inline exosome isolation and fluorescent detection using inertial manipulation of antibody-coated exosome capture beads from biological fluids.  相似文献   
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National undercount adjustment factors from the 1970 and 1980 U.S. censuses are used to prepare population projections for Ohio, which are in turn compared with unadjusted projections. "The findings suggest that decisions concerning adjustment factors have varying effects on short-term, long-term, and strategic forecasting. These effects are particularly salient for selected age-groups and the impact on state government budget decisions typically associated with these age-groups. We recommend that the effects of alternative adjustment possibilities be examined by state demographic centers and budget offices."  相似文献   
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The focus of this paper is on the current developments in science education occurring in the posthumously built Homi Bhabha Centre for Science Education in Mumbai and to offer context for various indigenous developments that are shaping science education in India today. In this paper, I describe the story of Homi Bhabha and his rich legacy of India’s atomic energy program. Specifically, I focus on the institutions built by Homi Bhabha, including the Tata Institute of Fundamental Research and the Bhabha Atomic Research Centre (BARC) and I examine how these institutions have enabled Indian scientists to contribute to the advancement of science knowledge in the world.  相似文献   
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Digital government is universally gaining acceptance as the public becomes more technologically advanced. It is critical for the government to embrace new technology for minimizing costs and maximizing utility of services to the taxpayers. While administrative services have been easily ported to the digital world, there are still many important citizen-centric services that have not yet been effectively migrated. Quick Response codes (QR codes) provide a means to effectively distribute many different varieties of information to the public. We propose to integrate QR code systems and corresponding smartphone applications into existing government services with the goal of providing a new level of interactivity for the public. We illustrate this through two case studies, examining the National Park Services and the Mobile Environmental Information Services (MENVIS). The focus is on developing a QR code waypoint system for park navigation, as well as incentivizing park use through gamification of site attractions. The system provides increased safety for park goers, disseminates information more effectively and accurately, and improves feedback.  相似文献   
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Teaching quantitative subjects such as operations management (OM) can be quite challenging. In this article, we present a novel approach that uses simplified concept maps for teaching OM. This application of concept maps was investigated to determine if it helps students to answer questions and to solve OM problems more effectively. Our study used a controlled experimental design with students divided into two groups, one taught using concept maps and another group taught using traditional techniques. Student learning was measured with pre‐ and posttests consisting of both multiple‐choice and constructed‐response items. The performance of the two groups was compared using an independent samples t‐test and analysis of covariance to control for the covariate “pretest.” The results indicate that use of simplified concept mapping significantly improved student learning of OM course material. We therefore recommend its adoption as an active‐learning pedagogical technique that can lead to positive change in the OM classroom.  相似文献   
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This paper details the findings from a study of airline compliance with Department of Transportation (DOT) regulations requiring that persons with disabilities not be discriminated against in the pricing of airline travel. These regulations mandate that if an airline website is inaccessible for persons with disabilities, the airline must charge the same price that is available on the website and may not charge a fee for purchasing tickets over the phone. To evaluate compliance, the websites of leading airlines were examined for accessibility in terms of the ability to check flight schedules and order tickets. Among the four airlines with barriers to accessibility on their websites, a series of phone calls were made by researchers to assess whether the DOT regulations would be followed. Two of the airlines, USAirways and United, practiced discriminatory pricing, even after being made aware of the regulations, in over one-third of the phone calls. This paper details the findings from the study and analyzes the data in terms of website accessibility, civil rights for travelers with disabilities, and policy implications.  相似文献   
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Enzymology is a diagnostic indicator for myocardial infarction and diabetes in hypertension patients. Therefore the selection of methods for measurement of cardiac enzyme, Aspartate transaminase (AST), Creatine kinase(CK), and isoenzyme of creatine kinase (MB form), determine the effectiveness of antihypertension drug would provide the physician with diagnostic and prognostic clinical evidence.  相似文献   
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