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Cramer JT Beck TW Housh TJ Massey LL Marek SM Danglemeier S Purkayastha S Culbertson JY Fitz KA Egan AD 《Journal of sports sciences》2007,25(6):687-698
The aims of this study were to examine the acute effects of static stretching on peak torque, work, the joint angle at peak torque, acceleration time, isokinetic range of motion, mechanomyographic amplitude, and electromyographic amplitude of the rectus femoris during maximal concentric isokinetic leg extensions at 1.04 and 5.23 rad x s(-1) in men and women. Ten women (mean +/- s: age 23.0 +/- 2.9 years, stature 1.61 +/- 0.12 m, mass 63.3 +/- 9.9 kg) and eight men (age 21.4 +/- 3.0 years, stature 1.83 +/- 0.11 m, mass 83.1 +/- 15.2 kg) performed maximal voluntary concentric isokinetic leg extensions at 1.04 and 5.23 rad x s(-1). Following the initial isokinetic tests, the dominant leg extensors were stretched using four static stretching exercises. After the stretching, the isokinetic tests were repeated. Peak torque, acceleration time, and electromyographic amplitude decreased (P< or = 0.05) from pre- to post-stretching at 1.04 and 5.23 rad . s(-1); there were no changes (P > 0.05) in work, joint angle at peak torque, isokinetic range of motion, or mechanomyographic amplitude. These findings indicate no stretching-related changes in the area under the angle - torque curve (work), but a significant decrease in peak torque, which suggests that static stretching may cause a "flattening" of the angle - torque curve that reduces peak strength but allows for greater force production at other joint angles. These findings, in conjunction with the increased limb acceleration rates (decreased acceleration time) observed in the present study, provide tentative support for the hypothesis that static stretching alters the angle - torque relationship and/or sarcomere shortening velocity. 相似文献
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In this work, we introduce a method for the soft-lithography-based fabrication of rigid microstructures and a new, simple bonding technique for use as a continuous-flow cell lysis device. While on-chip cell lysis techniques have been reported previously, these techniques generally require a long on-chip residence time, and thus cannot be performed in a rapid, continuous-flow manner. Microstructured microfluidic devices can perform mechanical lysis of cells, enabling continuous-flow lysis; however, rigid silicon-based devices require complex and expensive fabrication of each device, while polydimethylsiloxane (PMDS), the most common material used for soft lithography fabrication, is not rigid and expands under the pressures required, resulting in poor lysis performance. Here, we demonstrate the fabrication of microfluidic microstructures from off-stoichiometry thiol-ene (OSTE) polymer using soft-lithography replica molding combined with a post-assembly cure for easy bonding. With finite element simulations, we show that the rigid microstructures generate an energy dissipation rate of nearly 107, which is sufficient for continuous-flow cell lysis. Correspondingly, with the OSTE device we achieve lysis of highly deformable MDA-MB-231 breast cancer cells at a rate of 85%, while a comparable PDMS device leads to a lysis rate of only 40%. 相似文献
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Anu Jain Sumanth Kumar Mallupattu Reetu Thakur Satyawati Mohindra Amanjit Bal Ashim Das Sushmita Ghoshal Arnab Pal 《Indian journal of clinical biochemistry : IJCB》2021,36(3):288
Cripto-1 (CR-1) is an oncofetal protein with its role as a key factor in early process of carcinoma has been evaluated in cases of various cancers. However, very few studies have reported its role in oral cancer, which is the sixth most common cancer around the world, particularly with high prevalence in developing countries. Oral squamous cell carcinoma (OSCC) is the most predominant (90%) of all the histological types of oral cancer. Late detection, associated with increased morbidity and mortality, is mainly attributed to non-availability of a suitable biomarker for the disease. In the present pilot study, we have evaluated the role of soluble CR-1, in serum as a potential tumor marker for OSCC. CR-1 was estimated using sandwich ELISA in serum samples of 50 biopsy proven OSCC patients (pre and post treatment) along with age and gender matched healthy controls. Immunohistochemistry was also done in corresponding tumor tissue sections to check the expression of CR-1. Pre-treatment CR-1 was found to be 2.25-fold higher in serum of OSCC patients as compared to control (p < 0.0001***), which was reduced to 1.6 folds post treatment (p = 0.0006***). CR-1 levels were comparatively higher in early stage of disease. Upon IHC 80% of the cases were found to be positive for CR-1. This study provides evidence that serum levels of CR-1 are elevated in patients of Oral Squamous Cell Carcinoma, which decrease post treatment. Also, the association of expression of protein with tumor progression predicts CR-1 as a molecule that can be further evaluated as a potential tumor maker in OSCC. 相似文献
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On 29 September 2016, the Indian army conducted a surgical strike along the India–Pakistan border. The mainstream news media in India followed the event with assertive nationalistic rhetoric. What was supposed to be a covert military operation against terrorism became morphed into political rhetoric aggravated by the unwarranted jingoism of television news channels and social media. The coverage of the strike on television news is typically characterized by a confluence of militant nationalist discourses, and the ideologically imbued labelling of specific communities. Within this context, drawing from the close reading of the coverage, this article analyses how Indian television news sustains the construction of a fictive “we”, conflated with the government policies and military strategies, and speaks for a supposedly homogeneous national consensus that also consciously obscures the dissent through minority voices. The article emphasizes the relationship between communities, formal politics, and the supposedly non-political spaces and practices of news media in India. 相似文献
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Sushmita Mitra 《Open Learning》2013,28(3):255-265
This paper identifies the key factors that contribute to the Open School in India students' satisfaction, considering student support elements at pre‐entry, start up, learning, evaluation and certification and after certification phases. The study adapted Rekkedal and Eriksen's importance‐satisfaction model to recognise areas that are important to students as well as their degree of satisfaction with each attribute. It is found that the student group considered is generally satisfied with the support elements that they perceive to be important and there is a strong positive linear relationship (r =0.83) between importance and satisfaction. However, according to the group, priority needs to be given to personal contact programmes in the study centres, online tutorials and feedback on assignments, which are three prime support elements in the learning phase. 相似文献
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Frame loss error concealment for SVC 总被引：2，自引：0，他引：2
INTRODUCTION Real-time transmission of video data in network environments, such as wireless and Internet, is a challenging task, as it requires coding efficiency, network friendliness and error robustness. Scalability is a possible solution for network adaptive applica- tions. The Scalable Extension of H.264/AVC (SVC) (JVT of ISO/IEC MPEG & ITU-T VCEG, 2005b) aims at achieving both high compression performance and adaptivity for video delivery over heterogeneous networks. SVC… 相似文献