排序方式： 共有83条查询结果，搜索用时 15 毫秒
1.
2.
Luca Lanotte Giovanna Tomaiuolo Chaouqi Misbah Lionel Bureau Stefano Guido 《Biomicrofluidics》2014,8(1)
The confined flow of red blood cells (RBCs) in microvasculature is essential for oxygen delivery to body tissues and has been extensively investigated in the literature, both in vivo and in vitro. One of the main problems still open in microcirculation is that flow resistance in microcapillaries in vivo is higher than that in vitro. This discrepancy has been attributed to the glycocalyx, a macromolecular layer lining the inner walls of vessels in vivo, but no direct experimental evidence of this hypothesis has been provided so far. Here, we investigate the flow behavior of RBCs in glass microcapillaries coated with a polymer brush (referred to as “hairy” microcapillaries as opposed to “bare” ones with no coating), an experimental model system of the glycocalyx. By high-speed microscopy imaging and image analysis, a velocity reduction of RBCs flowing in hairy microcapillaries as compared to bare ones is indeed found at the same pressure drop. Interestingly, such slowing down is larger than expected from lumen reduction due to the polymer brush and displays an on-off trend with a threshold around 70 nm of polymer brush dry thickness. Above this threshold, the presence of the polymer brush is associated with an increased RBC deformation, and RBC velocity is independent on polymer brush thickness (at the same pressure drop). In conclusion, this work provides direct support to the hypothesis that the glycocalyx is the main factor responsible of the higher flow resistance found in microcapillaries in vivo. 相似文献
3.
4.
张广宇 《岳阳职业技术学院学报》2009,24(4):24-26
高职院校实施全员竞聘,是人力资源管理改革的有益尝试.全员竞聘是顺应高职教育发展大势的迫切需要、促进各项事业发展的迫切要求、广大教职工的迫切愿望,实施过程中应坚持因校制宜、因事设岗、因人而异的原则.全体教职工应本着时事业、对组织负责的态度来理解、支持、参与和配合学院做好这项工作. 相似文献
5.
6.
处于东汉晚叶的文学家蔡邕受到社会形势特别是辞赋创作实际的影响,通过创作和理论引导把辞赋从经学控制中抽离出来,使之不再担任"匡国理政"的重任,而更多的走向个体人生,走向世俗情感,走向"聊以游意",回归文学的审美本质。蔡邕对辞赋的创作肯定态度、对辞赋审美愉悦功能的肯定、从艺术层面的分类以及内容上情怀的抒写构成了一个比较完善的赋学理论体系,对东汉晚叶以及建安时期甚至整个中国古代的文学创作与文学理论发展产生了重要影响,具有一定的价值意义。 相似文献
7.
王育洁 《衡阳师范学院学报》2014,(5):118-123
非范畴化是指为在一定的条件下,范畴成员逐渐失去范畴特征的过程。这些成分在重新范畴化之前处于一种不稳定的中间状态,它们丧失了原有范畴的某些典型特征,同时获得了新范畴的某些特征。以非范畴化理论为依据,探讨日语复合动词的构成要素在非范畴化阶段的副词化现象。从意义上看,复合动词副词化的构成要素在副词化过程中丧失了原意,获得了加强主要动词动作的程度副词意;从句法特征上看,副词化的构成要素丧失格支配能力。 相似文献
8.
唐芳贵 《衡阳师范学院学报》2014,(5):141-143
心理健康教育渗透是解决高师公共心理学教学内容枯燥、教学方法单调、严重脱离教育和生活实际等问题的有效途径。基于重要性认识,提出了准确定位、目标融合,案例教学、体验为主,创新模式、三助为体等渗透路径,以及加强教材建设和师资培训等保障措施。 相似文献
9.
放射性核素的临床应用及研究已历数十载,已有碘-131、磷-32、锶-90及钇-90等众多放射性核素被成功用于治疗良恶性疾病。随着新的放射性核素及药物不断应用于骨转移瘤疼痛治疗、神经内分泌肿瘤及其他良恶性肿瘤治疗,放射性核素治疗得到了快速发展。目前,放射性核素治疗已进入蓬勃发展期;在亚洲,由于甲状腺和肝脏肿瘤的高发病率,促进了放射性核素治疗及其靶向治疗研究的日益发展。随着放射性核素与其他药物的联合应用,放射性核素治疗肿瘤的临床价值必将显著提高。 相似文献
10.