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Early childhood is a sensitive period for learning and social skill development. The maturation of cerebral regions underlying social processing lays the foundation for later social-emotional competence. This study explored myelin changes in social brain regions and their association with changes in parent-rated social-emotional development in a cohort of 129 children (64 females, 0–36 months, 77 White). Results reveal a steep increase in myelination throughout the social brain in the first 3 years of life that is significantly associated with social-emotional development scores. These findings add knowledge to the emerging picture of social brain development by describing neural underpinnings of human social behavior. They can contribute to identifying age-/stage-appropriate early life factors in this developmental domain. 相似文献
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As medical programs place increasing importance on competency-based training and surgical simulations for residents, anatomy laboratories, and body donation programs find themselves in a position of adapting to changing demands. To better assess the demand for “life-like” cadaveric specimens and evaluate the possible impacts that competency-based medical education could have upon the body donation program of McGill University, Canada, the authors tracked, over the course of the last 10 years, the number of soft-embalmed specimens, along with the number of teaching sessions and the residents enrolled in competency-based programs that are using cadaveric material. The results reveal that the number of soft-embalmed specimens used within residency training increased from 5 in 2009 to 35 in 2019, representing an increase from 6% of bodies to 36.5% of the total number of body donors embalmed in this institution. Correspondingly, the number of annual teaching sessions for residents increased from 19 in 2012 to 116 in 2019. These increases in teaching are correlated with increasing number of residents enrolled in competency-based programs over the last 3 years (Pearson r ranging from 0.9705 to 0.9903, and R2 ranging from 0.9418 to 0.9808). Those results suggest that the new skill-centered curricula which require residents to perform specific tasks within realistic settings, exhibit a growing demand for “life-like” cadaveric specimens. Institutions’ body donation programs must, therefore, adapt to those greater need for cadaveric specimens, which presents many challenges, ranging from the logistical to the ethical. 相似文献
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Jonathan J. Mallett 《Learned Publishing》2021,34(1):49-56
- Scientific publication has been a key part of the scientific method since the inception of Philosophical Transactions in 1665.
- The scientific publications industry has grown exponentially along with science, incorporating technological innovations along the way, and adapting journal processes and practices to changing needs of science as it matured.
- Of all the technological innovations over more than 300 years, the move to online journals may be the most significant, making open access to content practical for the first time.
- The open‐access movement is disrupting the economics of journal publishing, which is hoped will make the industry more competitive: the ability of the publications industry to adapt to open access will be a measure of its resilience.
- The demand for articles published in reputable journals continues to grow as readers trust the credibility of peer reviewed journal articles, and good authors value the prestige of publishing in the best journals.
- It is difficult to predict what new functionalities may be included in articles of the future or what additional services publishers and editors will provide, but there is every reason to believe that scientific journal articles are here to stay.
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David Sánchez-Oliva Rebecca M. Leech Alberto Grao-Cruces Irene Esteban-Cornejo Carmen Padilla-Moledo Oscar L. Veiga 《Journal of sports sciences》2020,38(9):1062-1069
ABSTRACTThe aims of this study were to identify profiles of sedentary behaviour (SB) patterns, based on leisure-time self-reported SB modalities (screen, educative, social, and relaxing) and to evaluate changes in these profiles over 2 years among Spanish youth aged 8–18 years. Latent profile analysis (LPA), a data-driven analytic approach, was used to identify groups of boys and girls (n = 1553; 48% girls; mean±SD age: 12.56 ± 2.49 y) with distinct SB profiles using the SB modalities (time/d) as input variables. Latent transition analysis, an extension of LPA that uses longitudinal data, was used to analyse 2-year changes in these profiles. At baseline, four and three SB profiles were found among boys (labelled: screen, educative, social, and relaxing) and girls (labelled: screen/social, educative, and relaxing), respectively. Overall, more girls (range: 48%-67%) had the same profile over time, than boys (40%-52%). Participants with a screen or relaxing SB profile at baseline were more likely to have an educative profile after 2 years. Youth with a social and an educative SB profile at baseline were more likely to transition to profiles characterized by higher screen and social SB, respectively. Using a novel and person-centered approach, this study identified gender-specific SB profiles that were moderately stable over time. 相似文献
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Anthony J. Sadar 《Science & Education》2018,27(1-2):233-235
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基于深度学习的中文专利自动分类方法研究 总被引：2，自引：0，他引：2
[目的/意义] 面向当前国内专利审查和专利情报分析工作中对于海量专利分类的客观需求，设计了7种基于深度学习的专利自动分类方法，对比各种方法的分类效果，从而助力专利分类效率和效果的提升。[方法/过程] 针对传统机器学习方法存在的缺陷，基于Word2Vec、CNN、RNN、Attention机制等深度学习技术，考虑专利文本语序特征、上下文特征以及分类关键特征，设计Word2Vec+TextCNN、Word2Vec+GRU、Word2Vec+BiGRU、Word2Vec+BiGRU+TextCNN等7种深度学习模型，以中国专利为例，选取IPC主分类号的"部"作为分类依据，对比这7种模型与3种传统分类模型在中文专利分类任务中的效果。[结果/结论] 实证研究效果显示，采用考虑语序特征、上下文特征及强化关键特征的深度学习方法进行中文专利分类具有更优的分类效果。 相似文献
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[目的/意义] 通过构建二模复杂网络模型，揭示隐藏在海量文献中的隐性知识。[方法/过程] 通过NetworkX复杂网络工具包，依据任意两个节点的共现关系构建二模复杂网络模型；对网络模型中节点的共现关系进行加权，计算网络的拓扑信息并进行AP聚类，提取节点间的直接关系；采用AUC方法对AA、JC、加权改进的wAA和wJC等4种链路预测算法进行评价，遴选出最合适的预测算法，并对复杂网络的隐性关系进行预测分析。[结果/结论] 以潜在药物靶点挖掘为例进行的实证研究结果表明，wAA链路预测算法为最优的链路预测算法；二模复杂网络模型、指标和方法体系在美国化学文摘社数据库中的药物靶点挖掘中具有一定的有效性。下一步计划在其他数据库中或其他研究领域中进行尝试，以进一步验证该模型的通用性和有效性。 相似文献
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