The neural correlates of working memory training in typically developing children     

Jonathan S. Jones  Anna-Lynne R. Adlam  Abdelmalek Benattayallah  Fraser N. Milton 《Child development》2022,93(3):815-830

Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.  相似文献   

Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)     

Fadhaa A. Ghafil  Bassim I. Mohammad  Hussain S. Al-Janabi  Najah R. Hadi  Hayder A. Al-Aubaidy 《Indian journal of clinical biochemistry : IJCB》2021,36(1):81

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.  相似文献   

Digital Module 16: Longitudinal Data Analysis     

Jeffrey R. Harring  Tessa L. Johnson 《Educational Measurement》2020,39(3):137-138

In this digital ITEMS module, Dr. Jeffrey Harring and Ms. Tessa Johnson introduce the linear mixed effects (LME) model as a flexible general framework for simultaneously modeling continuous repeated measures data with a scientifically defensible function that adequately summarizes both individual change as well as the average response. The module begins with a nontechnical overview of longitudinal data analyses drawing distinctions with cross-sectional analyses in terms of research questions to be addressed. Nuances of longitudinal designs, timing of measurements, and the real possibility of missing data are then discussed. The three interconnected components of the LME model—(1) a model for individual and mean response profiles, (2) a model to characterize the covariation among the time-specific residuals, and (3) a set of models that summarize the extent that individual coefficients vary—are discussed in the context of the set of activities comprising an analysis. Finally, they demonstrate how to estimate the linear mixed effects model within an open-source environment (R). The digital module contains sample R code, diagnostic quiz questions, hands-on activities in R, curated resources, and a glossary.  相似文献   

Getting What You Pay For: Children's Use of Market Norms to Regulate Exchanges     

Margaret Echelbarger  Susan A. Gelman  Charles W. Kalish 《Child development》2019,90(6):2071-2085

Children are sensitive to a number of considerations influencing distributions of resources, including equality, equity, and reciprocity. We tested whether children use a specific type of reciprocity norm—market norms—in which resources are distributed differentially based strictly on amount offered in return. In two studies, 195 children 5–10 years and 60 adults distributed stickers to friends offering same or different amounts of money. Overall, participants distributed more equally when offers were the same and more unequally when offers were different. Although sensitive to why friends offered different amounts of money, children increasingly incorporated market norms into their distributions with age, as the oldest children and adults distributed more to those offering more, irrespective of the reasons provided.  相似文献   

Food (in)security communication: a Journal of Applied Communication Research forum addressing current challenges and future possibilities     

Megan K. Schraedley  Hamilton Bean  Sarah E. Dempsey  Mohan J. Dutta  Kathleen P. Hunt  Sonia R. Ivancic 《Journal of Applied Communication Research》2020,48(2):166-185

ABSTRACT

This forum brings together food, (in)security, and communication. The authors participating in this forum center communication as both process and tool for understanding, mitigating, and making meaning of food (in)security. The nine authors together discuss the role of communication in food (in)security, the central challenges for scholars and practitioners working on food (in)security, and the creative possibilities and impacts influencing the future of food (in)security. The forum produces a call for applied scholars to re-imagine communication frameworks in order to make meaningful differences in their communities.  相似文献   

中国竞技体育人力资源相关问题探讨   总被引：5，自引：0，他引：5  

肖林鹏  赵云宏  张兆青  骆意 《广州体育学院学报》2003,23(6):8-9

对竞技体育人力资源的概念、特点等问题进行了探讨：研究表明，竞技体育人力资源是指竞技体育发展所需人员的现实及潜在禀赋的总和。处于不同层次、不同领域的众多人员组成了竞技体育人力资源系统：竞技人力资源具有稀缺性、目标性、整体性及调控性等特点.  相似文献   

国内运动生物力学发展现状思考   总被引：5，自引：0，他引：5  

王今越  刘伟  陈民盛 《天津体育学院学报》2003,18(4):33-36

运动生物力学是一门新兴的边缘性科学，其定义、研究范畴、研究方法都有待商榷。从这三个角度出发，主要对大量资料进行归纳总结，综合、概括了目前国内运动生物力学发展状况。力求对我国的运动生物力学发展的状况勾勒出一个清晰的脉络图，以便在这门学科今后的研究中减少盲目性，具有更强的实用性。  相似文献   

奥运会的经济价值分析以及对北京举办奥运会的借鉴意义   总被引：11，自引：1，他引：10  

马涛  赵宏 《天津体育学院学报》2003,18(3):15-17

2008年北京奥运会的举行将大大加快北京地区乃至我国的经济现代化建设的步伐。应用实证研究的方法，对历届奥运会的经济价值进行分析，指出举办奥运会对促进北京地区乃至全国的经济增长、改善劳动力就业，加快产业结构调整的积极作用。同时从资金筹措、场馆建设、产业可持续发展等方面对北京避免奥运会后可能出现的“经济低谷效应”，实现可持续发展提出了建议。  相似文献   

网络型电子期刊编目原则探讨   总被引：12，自引：0，他引：12  

沈芸芸  张广钦 《大学图书馆学报》2003,21(3):79-82

网络型电子期刊的编目原则问题是进行该类型资源编目首先要解决的问题,本文针对网络型期刊的特点探讨了两种原则以及相应的著录要求,即:单记录原则(在印刷版/原始记录中给出访问路径);为网络版期刊单独建立记录的原则。笔者建议采用后者,并讨论了网络型电子期刊的著录信息源的选取。  相似文献   

体育课教学质量评估研究     

毕研洁  周志强  史琦兰 《天津体育学院学报》2003,18(1):75-76

评价一堂体育课，总要有几条简明扼要的标准。传统的评价标准在一定阶段促进了我国学校体育的发展，但在实施素质教育的今天，已不能完全适应时代的要求，有时甚至阻碍了素质教育的发展。一堂好的体育课要作到全力引导全体学生参与，提高学生参加活动兴趣，使其有愉快的心理体验。同时保证教学的目标、教材、手段相配套，课堂教育的度、量、序安排科学，这样才能建立师生间民主合作的人际关系。１研究对象和方法１．１研究对象笔者对兰州大学２０００、２００１级文理科各１２００名男女学生进行问卷调查，年龄均在１８～２０岁之间。调查后…  相似文献