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1.
The effects of writing style upon mature older readers’ reading comprehension are considered. Two narrative historical selections, the first emotive and abstract and the second nonemotive and concrete, were employed. Miscue analysis was used to evaluate the efficiency with which each reader used reading strategies across the five systems that cue meaningful comprehension. Miscues were analyzed at the word, clause, sentence, and intersentence levels. In addition, interview schedules were employed to identify readers’ perceptions of preferred reading strategies and to permit a comparison with actual performance. The findings indicate that mature older readers are consistent in cue system utilization. A preference for the word cue system influenced both the use of cues from other systems and comprehension. Use of the word‐level cue system is inversely related to the use of the other available cue systems. Preference for cues within words also appears to be inversely related to comprehending effectiveness. The subjects’ perceptions of the reading process and their actual reading performance appeared to determine patterns of cue system use more clearly than did the differences in materials. As a result, those developing materials intended for use in programs with older persons should not only be concerned with the content and quality of those materials but also the skills and perceptions of those who will use the materials.  相似文献   
2.

Introduction:

Two Italian adults arrived at the Emergency Department referring diarrhea, nausea and vomiting for 4 days; weakness, fatigue and visual hallucinations were also complained of. Patients reported the ingestion of some leaves of a plant, which they supposed to be “donkey ears”, a week before. Physical examination showed hypotension and bradycardia and ECG examination disclosed sinus rhythm and repolarization abnormalities (scooping of the ST-T complex) in both patients and a 2:1 AV block in the man.

Materials and methods:

Digoxin concentration was evaluated twice for each patient (at the admission and after 4 hours) by the automated immunoassay system ADVIA Centaur®. Digitoxin concentration was evaluated by liquid chromatography-mass spectrometry (LC-MS/MS).

Results:

Despite clinical picture was suggestive of digitalis intoxication, digoxin levels were undetectable. Due to the more severe clinical picture, the male patient was treated with anti-digoxin antibodies (Digifab®) achieving a good clinical improvement and remission of the AV block within two hours. Initial diagnosis was confirmed by LC-MS/MS showing high digitoxin concentrations, but digoxin was undetectable. Patients remained stable and 48 hours later were discharged from the hospital.

Conclusion:

Whereas digoxin determination frequently relies on monoclonal antibodies which do not cross-react to digitoxin, polyclonal antibodies constituting Digifab® recognize a large spectrum of cardiac glycosides, including digitoxin. This report emphasizes the primary role of the clinical approach to patients in the emergency setting and how an active communication and a continuous sharing of professional experiences between Laboratory and Clinicians ensure an early and correct diagnosis.  相似文献   
3.
Increasingly, metadata standards have been recognized as constructed rather than neutral. In this article, we argue for the importance of a documentation approach to metadata standards creation as a codification of this growing recognition. By making design decisions explicit, the documentation approach dispels presumptions of neutrality and, drawing on the “wicked problems” theoretical framework, acknowledges the constructed nature of standards as “clumsy solutions.”  相似文献   
4.
This study utilized early reading assessment data from a randomized trial of 210 urban and rural schools in Texas to examine contextual effects on risk prediction in first and second grade. The primary objective was to examine the roles of (a) individual differences, (b) the grade 1 classroom, and (c) the pairing of first and second grade teachers in determining grade 2 outcomes in word reading and fluency. A second objective was to investigate whether the administration format of the assessment (paper, paper plus desktop, handheld plus desktop) or the level of teacher support (web mentoring, no mentoring) moderated the prediction. These moderator variables proved not to be significant. Subsequent analyses found that a combination of student pretest and mean of pretest classroom was a better predictor than student pretest alone. Additionally, the effect of student scores varied by teacher-pair. On average, intraclass correlations (ICCs) ranged from 6% to 17%. Differences in ICCs at the classroom level were much greater than at the school level, and differences in urban schools were twice that of rural schools.  相似文献   
5.
Pigeons were trained to match temporal (2 and 8 sec of keylight) and color (red and green) samples to vertical and horizontal comparison stimuli. In Experiment 1, samples that were associated with the same correct comparison stimulus displayed similar retention functions; and there was no significant choose-short effect following temporal samples. This finding was replicated in Phase 1 of Experiment 2 for birds maintained on the many-to-one mapping, and it was also obtained in birds that had been switched to a one-to-one mapping by changing the comparison stimuli following color samples. However, in Phase 2 of Experiment 2, when the one-to-one mapping was produced by changing the comparison stimuli following temporal samples, a significant choose-short effect was observed. In Experiment 3, intratrial interference tests gave evidence of temporal summation effects when either temporal presamples or color presamples preceded temporal targets. This occurred even though these interference tests followed delay tests that failed to reveal significant choose-short effects. The absence of significant choose-short effects in Experiment 1 and in Phase 1 of Experiment 2 indicates that temporal samples are not retrospectively and analogically coded when temporal and nontemporal samples are mapped onto the same set of comparisons The interference test results suggest that the temporal summation effect arises from nonmemorial properties of the timing system and is independent of the memory code being used  相似文献   
6.
A comparison of the effects of scopolamine hydrobromide on working memory and reference memory in White Carneaux pigeons was undertaken by means of a modified delayed matching-to-sample procedure. Performance on working-memory trials was disrupted by decreases in sample duration and intertriai interval and by increases in delay interval. Performance on reference memory trials was not disrupted by any of these parametric manipulations. In Experiment 1, the pigeons received injections of scopolamine hydrobromide (0.01, 0.05, or 0.1 mg/kg), scopolamine methyl bromide (0.1 mg/kg), or saline prior to test sessions. In Experiment 2, the pigeons received injections of scopolamine hydrobromide (0.01 or 0.03 mg/kg), scopolamine methyl bromide (0.03 mg/kg), or saline. In both experiments, scopolamine hydrobromide had greater disruptive effects on working-memory trials than on reference-memory trials. The centrally active form of scopolamine disrupted working-memory trial accuracy more than the peripherally active form. However, no drug dose × delay interval interaction was obtained. Thus, the interference on working-memory-trial accuracy produced by central cholinergic blockade would not appear to be due to alterations in the active maintenance of information during the delay interval.  相似文献   
7.
Pigeons were trained in a two-choice delayed matching-to-sample task with red and green hues. A brief postsample cue (a vertical or horizontal line) signaled whether the comparison stimuli would be presented or omitted on each trial. Comparison stimuli were always presented following the remember-cue (R-cue) trial, but never following the forget-cue (F-cue) and no-cue trials. In Experiment 1, matching accuracy on F-cue and no-cue trials was equivalent and was considerably inferior to accuracy on R-cue trials. In Experiment 2, the placement of the postsample cue was manipulated. Matching accuracy decreased as the R cue was delayed in the retention interval, but performance in the F-cue condition was not affected. These data indicate that the no-cue condition can function as an implicit F cue and that the R cue can function to initiate and maintain rehearsal.  相似文献   
8.
Pigeons were trained in a duration-comparison procedure to peck one key if the comparison duration (c) was 1 sec shorter than a standard duration (s), and another key if c was 1 sec longer than s. During training, the s-c delay was 1 sec, and the total duration of an s-c pair was not predictive of the correct choice. In Experiment 1, during equal-duration pair test trials, pigeons increasingly responded long (i.e., c τ s) as the s-c delay was lengthened. In Experiment 2, we demonstrated that s affected long responding on equal-duration test trials, even at the 8-sec s-c delay. In Experiment 3, long responding increased as the s-c delay was lengthened, even when stimulus conditions during the s-c delay differed from those during the intertrial interval (ITI). Additional analyses indicated that it was unlikely that the increase in long responding was due to the pigeons’ adding the s-c delay to c and comparing the total against the duration of s. The increase in long responding with an increase in s-c delay is more consistent with subjective shortening of s than with confusion between the s-c delay and the ITI.  相似文献   
9.
In Experiment 1, pigeons were trained to discriminate the duration (2 or 8 sec) of an empty interval separated by two 1325-Hz tone markers by responding to red and green comparison stimuli. During delay testing, a choose-short bias occurred at 1 sec, but a robust choose-long bias occurred at 9 sec. Responding in the absence of tone markers indicated that the pigeons were attending to the markers and not simply timing the total trial duration. The birds were then trained to match short (2-sec) or long (8-sec) empty intervals marked by light to blue/yellow comparisons. For both visual and auditory markers, delay testing produced a choose-short bias at 1 sec and a choose-long bias at 9 sec. In Experiment 2, the pigeons were shifted from a fixed to variable intertrial intervals (ITI) within sessions. On trials with tone markers, the duration of both the empty interval and the preceding ITI affected choice responding. On trials with light markers, only the duration of the empty interval influenced choice responding. Subsequent delay testing in the context of variable ITIs replicated the memory biases previously obtained. In Experiment 3, performance was assessed at various delay intervals on trials in which either the first or the second marker was omitted. The data from these omission tests indicated that the first marker initiated timing but that the second marker sometimes initiated the timing of a new interval. Explanations of these effects in terms of the internal clock model of timing are discussed, and a simple quantitative model of the delay interval data is tested.  相似文献   
10.
In environmental education the construction of appropriate knowledge is not enough, but is undoubtedly a fundamental component of individual and collective environmental responsiveness. The aim of this study was to investigate fifth graders' changes of conceptions about the greenhouse effect and global warming, due to socio‐cognitive interaction developed in small and large group discussions in an authentic classroom context during the implementation of an environmental education curriculum unit. We hypothesized that a classroom transformed into a community of discoursei.e. a learning environment which stimidates and supports giving verbal explanations, comparing and critically evaluating different points of view on the examined environmental phenomenon, would be a fruitful breeding ground for knowledge revision. The results show that classroom discussions, the core of the proposed learning activity, led the children, although at different levels, to the integration of new scientific knowledge into their conceptual ecology, based on the personal revision of pre‐instructional conceptions. As hypothesized, a high positive correlation was found between conceptual change and metaconceptual awareness of the changes in pre‐existing representations of the examined phenomenon. Some implications are drawn from the standpoint of environmental education.  相似文献   
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