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1.
Partha Chatterjee 《Inter-Asia Cultural Studies》2013,14(4):487-496
Abstract I wish to propose a general definition of empire that does not tie it with annexation and occupation of foreign territories and, therefore, is able to capture the new forms of indirect and informal control that have become common in recent decades. The imperial prerogative, I suggest, is the power to declare the colonial exception. Everyone agrees that nuclear proliferation is dangerous and should be stopped. But who decides that India may be allowed to have nuclear weapons, and also Israel, and may be even Pakistan, but not North Korea or Iran? We all know that there are many sources of international terrorism, but who decides that it is not Saudi Arabia or Pakistan but the regime of Saddam Hussein in Iraq that must be overthrown by force? Those who claim to decide on the exception are indeed arrogating to themselves the imperial prerogative. 相似文献
2.
We provide causal evidence that regulation induced product shocks significantly impact aggregate demand and firm performance in pharmaceutical markets. Event study results suggest an average loss between $569 million and $882 million. Affected products lose, on average, $186 million over their remaining effective patent life. This leaves a loss of between $383 million and $696 million attributable to declines in future innovation. Our findings complement research that shows drugs receiving expedited review are more likely to suffer from regulation induced product shocks. Thus, it appears we may be trading off quicker access to drugs today for less innovation tomorrow. Results remain robust to variation across types of relabeling, market sizes, and levels of competition. 相似文献
3.
Anteneh Ayanso Dipanjan Chatterjee Danny I. ChoAuthor vitae 《Government Information Quarterly》2011,28(4):522-532
E-Government has received significant attention as digital technologies transcend private businesses and serve as a basic source of transformation in government functions. One most notable project is the United Nations Public Administration Network (UNPAN) that assesses the e-Government readiness of the 192 member nations according to a quantitative composite index involving website assessment, telecommunication infrastructure, and human resource endowment. However, the UNPAN index, though rich in depth and breadth of data collection, relies on a method that is a simple mathematical average of the values of the variables measured. This paper revisits the UNPAN index and proposes alternative indices based on principal components analysis (PCA). Using the UNPAN survey data, four different versions of the index are presented and the resulting rankings of the nations are examined vis-à-vis the existing ranking. The theoretical and policy implications of the proposed methodology and its results are discussed. 相似文献
4.
Mala Mahto Baidarbhi Chakraborthy Srinivas H. Gowda Harneet Kaur Gaurav Vishnoi Pramod Lali 《Indian journal of clinical biochemistry : IJCB》2012,27(3):284-289
The implications of subclinical hypothyroidism (SCH) are many amongst which the most important is progression to overt hypothyroidism. Other debatable aspects are its association with cardiovascular risk, neuromuscular and psychiatric dysfunction, increased predisposition to developing metabolic syndrome and an underlying pro-inflammatory state. We aimed to study the lipid profile, lipoprotein(a) [Lp(a)] and hsCRP levels and insulin resistance in a group of patients with SCH in a referral hospital and see if any significant differences exist between them and euthyroids. This is a case–control study where the selection of controls and cases was based on the thyroid profile. Subjects were selected on their visit to clinical biochemistry lab for thyroid function tests. 33 euthyroids were taken as controls (Group I) and 38 patients comprising of subclinical hypothyroids were grouped as cases (Group II). Serum thyroid stimulating hormone (TSH) was in the range of 0.5–5.0 mIU/L for euthyroids and for subclinical hypothyroids the concentration of TSH was more than 5 mIU/L. The concentration of tri-iodothyronine (T3) and thyroxine (T4) were in normal reference range in both the groups. Individual lipid profile parameters failed to show a significant p value between cases and controls. The LDL/HDL ratio was highly significant (p value < 0.0001) and hsCRP was also statistically between the two groups (p value = 0.0054). Lp(a) and insulin resistance did not differ significantly. SCH is a common disorder that frequently progresses to overt hypothyroidism. This study underlines the importance of LDL/HDL ratio rather than measurement of individual lipid profile parameters in bringing to light the dyslipidemic state associated with SCH. Moreover the use of hsCRP to detect an underlying pro-inflammatory state in SCH can also be emphasized. 相似文献
5.
This study examines how Muslim women use Internet-based media in the process of acculturation in the United States. Grounded theory methodology (Glaser, 1992) and Sam and Berry’s (2006) model of acculturation were used as theoretical and analytical frameworks. Semi-structured interviews were conducted with 14 Muslim women to learn about their media use and experiences in forming and maintaining relationships in the United States. Educational opportunities were an emerging theme in the determining factors of immigrating to the United States. The data indicated that Muslim women use a variety of Internet-based media such as Facebook, Skype, WhatsApp, Instagram, and Viber for communicating with family and friends locally and abroad. A majority of the participants reported that social media allowed them to express a part of their identities. The data suggests that the participants attained the level of acculturation defined as integration. The participants use these media to build and create relationships in their new communities. The combined relationships the participants maintain both locally and abroad seem to play a role in the creation of balance in their lives, which allows them to thrive in their new communities, at school, and at work. 相似文献
6.
Improvement of a system need not be the usual growth expected of dynamic systems. Decreasing variability, an important index of improvement, is discussed. The disappearance of 0.400 hitters from professional baseball can be better understood under such an assumption. Other examples illustrating the apparent paradox are also mentioned. 相似文献
7.
Neelima Verma Jyoti chakraverty Pankaj Baweja Alka Girotra Leena Chatterjee Manish Chugh 《Indian journal of clinical biochemistry : IJCB》2017,32(1):117-120
Hyperferritinemia (>10,000 ng/ml) is an important hallmark used as an indicator of infection triggered macrophage activation syndrome leading to hemophagocytic lympho histiocytosis (HLH). Measurement of serum ferritin can be used in diagnosis as well as disease monitoring indicator and prognosis related to HLH, cAPS, sepsis, neoplasm and inflammatory conditions. It is a major contributor to manage critically ill patients as predicting and monitoring indicator. It can be used as acute phase response in conditions of MAS, AOSD, cAPS etc. A case study in our hospital showed extremely high ferritin values along with low hemoglobin, elevated LDH and triglycerides with positive MRSA in sputum culture and macrophage proliferation and hemophagocytosis in the bone marrow examination. Patient showed definite inverse relation with steroid therapy and serum ferritin levels. 相似文献
8.
Shu-Ching Chen Min Chen Na Zhao Shahid Hamid Kasturi Chatterjee Michael Armella 《Government Information Quarterly》2009
Homeowner insurance rate making is an important public policy issue in the State of Florida. The State of Florida has over 2 trillion dollars of residential properties exposed to hurricane risk. The State has declared that it shall adopt public policy to encourage the use of sophisticated actuarial methods to assure that consumers are charged lawful insurance rates (Section 627.0628(1)(a)). To that effect, the State's insurance regulatory agency, the Florida Office of Insurance Regulation (OIR), sponsored the development of a Florida Public Hurricane Loss Model (FPHLM) to assess the risk and project insured residential losses. The FPHLM is an open and public model that has been developed primarily by university experts without influence from either the insurance industry or the state regulators. It is open to public scrutiny and provides an understandable baseline to check the assumptions as well as the outputs of the proprietary models. The FPHLM thus makes the rate evaluation process more objective and less political. It enables the state to justify rejecting or accepting rate increases based on an independent and transparent model, rather than a process that can be influenced politically. As a multi-disciplinary large scale research project with an iterative and incremental development cycle, the FPHLM system development and integration faced numerous challenges varying from technical factors to project management aspects. This paper will discuss the research experiences accumulated during the development of the FPHLM and the impact it has had on the homeowner insurance rate filing process in the State of Florida. 相似文献
9.
Gaurav Chikara Pramod Kumar Sharma Pradeep Dwivedi Jaykaran Charan Sneha Ambwani Surjit Singh 《Indian journal of clinical biochemistry : IJCB》2018,33(2):121-131
Prevalence of diabetes mellitus, a chronic metabolic disease characterized by hyperglycemia, is growing worldwide. The majority of the cases belong to type 2 diabetes mellitus (T2DM). Globally, India ranks second in terms of diabetes prevalence among adults. Currently available classes of therapeutic agents are used alone or in combinations but seldom achieve treatment targets. Diverse pathophysiology and the need of therapeutic agents with more favourable pharmacokinetic-pharmacodynamics profile make newer drug discoveries in the field of T2DM essential. A large number of molecules, some with novel mechanisms, are in pipeline. The essence of this review is to track and discuss these potential agents, based on their developmental stages, especially those in phase 3 or phase 2. Unique molecules are being developed for existing drug classes like insulins, DPP-4 inhibitors, GLP-1 analogues; and under newer classes like dual/pan PPAR agonists, dual SGLT1/SGLT2 inhibitors, glimins, anti-inflammatory agents, glucokinase activators, G-protein coupled receptor agonists, hybrid peptide agonists, apical sodium-dependent bile acid transporter (ASBT) inhibitors, glucagon receptor antagonists etc. The heterogeneous clinical presentation and therapeutic outcomes in phenotypically similar patients is a clue to think beyond the standard treatment strategy. 相似文献
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