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1.
Although much is known about adults’ ability to orient by means of cognitive maps (mental representations of the environment), it is less clear when this important ability emerges in development. In the present study, 97 seven- to 10-year-olds and 26 adults played a video game designed to investigate the ability to orient using cognitive maps. The game required participants to reach target locations as quickly as possible, necessitating the identification and use of novel shortcuts. Seven- and 8-year-olds were less effective than older children and adults in using shortcuts. These findings provide clear evidence of a distinct developmental change around 9 years of age when children begin to proficiently orient and navigate using cognitive maps.  相似文献   
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This paper stems from the observation that researchers in different fields tend to publish in different journals. Such a relationship between researchers and journals is quantitatively exploited to identify scientific community clusters, by casting the community detection problem into a co-clustering problem on bipartite graphs. Such an approach has the potential of leading not only to the fine- grained detection of scholar communities based on the similarity of their research activity, but also to the clustering of scientific journals based on which are the most representative of each community. The proposed methodology is purely data-driven and completely unsupervised, and does not rely on any semantics (e.g. keywords or a-priori subjective categories). Moreover, unlike “flat” data structures (e.g. collaboration graphs or citation graphs) our bipartite graph approach blends in a joint structure both the researcher's attitude and interests (i.e., freedom to select the venue where to publish) as well as the community's recognition (i.e., acceptance of the publication on a target journal); as such may perhaps inspire further scientometric evaluation strategies. Our proposed approach is applied to the Italian research system, for two broad areas (ICT and Microbiology&Genetics), and reveals some questionable aspects and community overlaps in the current Italian scientific sectors classification.  相似文献   
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Cossu  Giuseppe 《Reading and writing》2003,16(1-2):99-122
A case study of literacy acquisition in acongenitally speechless child (SM) isreported. In spite of a complete oral apraxia(due to bilateral focal brain damage), SMdeveloped normal intelligence and acquired complete mastery of reading and writing skills.Furthermore, both his verbal memory andmetaphonological skills were surprisinglypreserved. However, he showed a relativeimpairment in writing non-words. Theimplications of these findings for thedevelopmental interactions between language andliteracy are discussed.  相似文献   
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Unlike emotions, which are short-lasting events accompanied by viscero-motor responses, vitality forms are continuous internal states that modulate the motor behaviors of individuals and are devoid of the autonomic modifications that characterize real emotions. Despite the importance of vitality forms in social life, only recently have neurophysiological studies been devoted to this issue. The first part of this review describes fMRI experiments, showing that the dorso-central insula is activated during the execution, the perception and the imagination of arm actions endowed with different vitality forms as well as during the hearing and the production of speech conveying vitality forms. In the second part, we address the means by which the dorso-central insula modulates the networks for controlling action execution and how the sensory and interoceptive information is conveyed to this insular sector. Finally, we present behavioral data showing the importance of vitality forms in social interactions.  相似文献   
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Background

Due to the high prevalence of hemolysis in specimens received from the emergency department (ED), several strategies have been proposed to improve sample quality, but none of these seem effective to overcome the problem. In a preliminary study we showed that the use of S-Monovette blood collection system was effective to lower the risk of hemolysis in venous blood samples collected from intravenous catheters. This study was hence aimed to verify whether the replacement of a conventional vacuum system with S-Monovette may be effective to reduce the burden of hemolysis in the daily practice of a large urban ED.

Materials and methods

The study was divided in two observational periods of 4 months each. In the former period, blood was collected from intravenous catheters using BD Vacutainer SST II Plus plastic serum tubes, whereas in the latter period the blood was drawn from intravenous catheters using S-Monovette blood tubes in aspiration mode. Sample hemolysis was automatically assessed in all serum samples by photometrical measurement.

Results

The total number of hemolysed serum specimens was 624/14155 (4.41%) in the first phase of the study, and 342/13319 (2.57%) in the second phase of the study (P < 0.001).

Conclusion

Results of our study confirm that the introduction of the Sarstedt S-Monovette blood tubes has reduced the hemolysis rate in the emergency department compared to the previously used BD Vacutainer® SST II Plus plastic serum tubes.Key words: preanalytical phase, hemolysis, blood specimen collection, catheter, emergency department  相似文献   
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The paper applies a novel methodology to US and EPO patent data to assess how often the “general grace period” exception is used in the USA and the likely impact of international patent regulations that almost invariably deny such use on the pace of new disclosures in academia. Comparisons of average publication delays of European academic inventors show that the grace period accelerates knowledge communication and that variations are likely to depend on a lack of harmonisation of international legal systems, transaction costs and the presence of a firm among patent assignees.  相似文献   
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Preanalytical phase is the most vulnerable part of the total testing process and is considered to be among the greatest challenges to the laboratory professionals. However, preanalytical activities, management of unsuitable specimens and reporting policies are not fully standardized, nor harmonized worldwide. Several standards related to blood sampling and sample transportation and handling are available, but compliance to those guidelines is low, especially outside the laboratory and if blood sampling is done without the direct supervision of the laboratory staff. Furthermore, for some most critical procedures within the preanalytical phase, internationally accepted guidelines and recommendations as well as related quality measures are unfortunately unavailable. There is large heterogeneity in the criteria for sample rejection, the different strategies by which unacceptable samples are managed, processed and test results reported worldwide. Management of unacceptable specimens warrants therefore immediate harmonization. Alongside the challenging and long road of patient safety, preanalytical phase offers room for improvement, and Editors at Biochemia Medica Journal definitely hope to continue providing a respective mean for reporting studies on different preanalytical phase topics. With pleasure and delight we invite potential future authors to submit their articles examining the quality of various preanalytical activities to Biochemia Medica. We will keep nurturing this topic as our prominent feature and by this we hope to be able to deliver valid evidence for some future guidelines and recommendations.  相似文献   
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