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Thierry Mauban 《对外大传播》2008,(4):62-63
"双语视窗"栏目从2006年开办至今,已经走过了2年的历程,这些由在华外国友人撰写的小文章,以他们在华所见所闻为切入点,生动具体地反映出东西方观念、习俗的异同,也向我们提出了一个个既有趣又值得深思的问题。栏目一再连载得益于读者反馈中的正面回应。"不识庐山真面目,只缘身在此山中",换一个角度,从外国友人目光的折射中审视一下自己,更有助于全面地了解我们自身。同时,本栏目采用英汉对照形式,这些原汁原味的英文不仅有助于加深对作者原意的理解,也是一本学习现代英语的鲜活教材。 相似文献
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Throughout the world, the financing of education is in a state of crisis, a condition made even more acute by the simultaneous appearance of a doctrinal crisis with regard to the ends and the utility of education. For European higher education, the situation calls for the diversification of funding mechanisms. The public authorities, which up until now have borne most of the burden of higher education financing, must transfer a goodly portion of the burden to users, i.e., students and parents, and to the private sector. Various methods for financial diversification are explored as well as different formulae for user-financing. 相似文献
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Building on recent breakthroughs in the field of microfluidic-based capture of rare cancer cells circulating in the blood, the present article reports on the use of Herceptin functionalized PDMS devices designed to efficiently capture from blood cancer cells, overexpressing the tyrosine kinase human epidermal growth factor receptor (HER2). The identification of patients overexpressing HER2 is critical as it typically associates with an aggressive disease course in breast cancer and poor prognosis. Importantly, HER2 positive patients have been found to significantly benefit from Herceptin (Trastuzumab), a humanized monoclonal antibody (MAb) against HER2. Disposable PDMS devices prepared using standard soft lithography were functionalized by the plasma polymerization of an epoxy-containing monomer. The epoxy-rich thin film (AGEpp) thus created could be conjugated with Herceptin either directly or through a polyethylene glycol interlayer. The properties and reactivity toward the monoclonal antibody conjugation of these coatings were determined using x-ray photoelectron spectroscopy; direct conjugation provided a good compromise in reactivity and resistance to biologically nonspecific fouling and was selected. Using the breast cancer cell line SK-BR-3 as a model for cells overexpressing HER2, the immunocapture efficacy of the Herceptin functionalized PDMS was demonstrated in model studies. Validation studies confirmed the ability of the device to efficiently capture (～80% capture yield) HER2 positive cells from full blood. 相似文献
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We propose biofunctionalized nanofluidic slits (nanoslits) as an effective platform for real-time fluorescence-based biosensing in a reaction-limited regime with optimized target capture efficiency. This is achieved by the drastic reduction of the diffusion length, thereby a boosted collision frequency between the target analytes and the sensor, and the size reduction of the sensing element down to the channel height comparable to the depletion layer caused by the reaction. Hybridization experiments conducted in DNA-functionalized nanoslits demonstrate the analyte depletion and the wash-free detection ∼10 times faster compared to the best microfluidic sensing platforms. The signal to background fluorescence ratio is drastically increased at lower target concentrations, in favor of low-copy number analyte analysis. Experimental and simulation results further show that biofunctionalized nanoslits provide a simple means to study reaction kinetics at the single-pixel level using conventional fluorescence microscopy with reduced optical depth. 相似文献
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Statistical distributions in the production or utilization of information are most often studied in the framework of Lotkaian informetrics. In this article, we show that an Information Production Process (IPP), traditionally characterized by Lotkaian distributions, can be fruitfully studied using the effort function, a concept introduced in an earlier article to define an Exponential Informetric Process. We thus propose replacing the concept of Lotkaian distribution by the logarithmic effort function. In particular, we show that an effort function defines an Exponential Informetric Process if its asymptotic behavior is equivalent to the logarithmic function β · Log(x) with β > 1, which is the effort function of a Lotkaian distribution. 相似文献
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Reading and Writing - The present research studied the role of the non-executive and executive components of working memory in the detection of phonological, orthographical, and grammatical... 相似文献
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Robert J. Schinke Thierry Middleton Brennan Petersen Sanfu Kao Deborah Lefebvre Bahaa Habra 《Quest (Human Kinetics)》2019,71(2):163-174
ABSTRACTThere are varied approaches that have been used in sport for development (SFD) projects. This article is focused on the move by sport and exercise psychology researchers toward community-based SFD projects where marginalized groups are centralized. The authors have chosen two of their projects to exemplify different approaches to SFD. An initial project with an Aboriginal community is critically examined to reveal cultural missteps that perpetuated cultural colonization–something antithetical to community capacity building. The second project is then considered because of its closer alignment with cultural praxis and community capacity building. This second project focuses on the initial developments of a YMCA physical activity project designed to meet the needs of forced immigrants (a self-titled name developed by the refugee community members) and the staff who work with them. We culminate with five postulates proposed for SFD project teams derived from our vantage in sport and exercise psychology, where community engagement and eventual self-governance are imperatives. 相似文献
9.
Paul Craddock Jessica S. Wasserman Cody W. Polack Thierry Kosinski Charlotte Renaux Ralph R. Miller 《Learning & behavior》2018,46(2):171-181
Second-order conditioning (SOC; i.e., conditioned responding to S2 as a result of S1–US pairings followed by S2–S1 pairings) is generally explained by either a direct S2→US association or by an associative chain (i.e., S2→S1→US). Previous research found that differences in responses to S2 after S1 was extinguished often depended on the nature of the S2–S1 pairings (i.e., sequential or simultaneous). In two experiments with human participants, we examined the possibility that such differences result from S1 evoking S2 during extinction of S1 following simultaneous but not sequential S2–S1 pairings. This evocation of S2 by S1 following simultaneous pairings may have paired the evoked representation of S2 with absence of the outcome, thereby facilitating mediated extinction of S2. Using sequential S2-S1 pairings, both Experiments 1 and 2 failed to support this account of how extinction of S1 reduced responding to S2. Experiment 1 found that extinguishing S1 reduced responding to S2, while extinguishing S2 had little effect on responses to S1, although forward evocation of S1 during extinction of S2 paired the evoked representation of S1 with absence of the outcome. In Experiment 2, evocation of S2 during S1 nonreinforced trials was prevented because S2–S1 pairings followed (rather than proceeded) S1-alone exposures. Nevertheless, responding to S2 at test mimicked S1 responding. Responding to S2 was high in the context in which S1 had been reinforced and low in the context in which S1 had been nonreinforced. Collectively, these experiments provide additional support for the associative-chain account of SOC. 相似文献
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The usability of interactive whiteboards vs. computers was evaluated on three dimensions (visibility, legibility and comprehension) in the secondary school pupils. The visibility assessment consisted in detecting a visual stimulus varying in luminance using a staircase procedure, legibility was assessed with a target-search task, and we administered narrative and explanatory texts with or without illustrations to evaluate comprehension. The results of the visibility test showed that pupils found the light signal easier to detect on the IWB. For the legibility test, we observed differences in error rates and discriminability according to medium, font size and congruence between target and the distractor letters. Performances in the comprehension test were similar for both explanatory and narrative texts. Moreover, the presence of illustrations does not improve comprehension. These results could be related to the hierarchical structure of the texts, which facilitate comprehension. 相似文献