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In order to assess the etiology of reading disability as a function of mathematics performance, data from 168 monozygotic (MZ) and 127 same-sex dizygotic (DZ) twin pairs in which at least one member of each pair was reading-disabled were subjected to quantitative genetic analyses. MZ and DZ concordance rates for reading disability were computed for different levels of mathematics performance, and reading performance data were fitted to an extension of the basic multiple regression model for the analysis of selected twin data. Results of these analyses suggest that genetic factors may be especially salient as a cause of reading disability in children with borderline deficits in mathematics performance: thus, mathematics performance may be a valid dimension for diagnosing subtypes of reading disability. 相似文献
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Rebecca S. Betjemann Erik G. Willcutt Richard K. Olson Janice M. Keenan John C. DeFries Sally J. Wadsworth 《Reading and writing》2008,21(5):539-558
Longitudinal twin data were analyzed to investigate the etiology of the stability of genetic and environmental influences
on word reading and reading comprehension, as well as the stability of those influences on their relationship. Participating
twin pairs were initially tested at a mean age of 10.3 years, and retested approximately five years later. Both word reading
and comprehension were found to be highly stable, and genetic influences were primarily responsible for that stability. In
contrast to studies with younger participants, no unique genetic influences were observed at follow-up testing in this older
sample. High genetic correlations were obtained between word reading and reading comprehension at both ages, indicating common
genetic influences. However, significant genetic influence on comprehension was also observed, independent of that on word
reading. Although the phenotypic relation between the two measures appeared to decline across time, the genetic etiology of
this relation was highly stable. 相似文献
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髌股关节紊乱的病因分析探究 总被引：1，自引：0，他引：1
李奕 《首都体育学院学报》2005,17(3):108-112,123
髌股关节紊乱，以膝前痛为主要症状，是临床和体育运动中常见的膝关节疾患。对于其发病原因一直是争论的焦点，了解其发病原因对该病的诊断和治疗有积极作用。 相似文献
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The primary objectives of the present study are to introduce the Colorado Longitudinal Twin Study of Reading Disability, the
first longitudinal twin study in which subjects have been specifically selected for having a history of reading difficulties,
and to present some initial assessments of the stability of reading performance and cognitive abilities in this sample. Preliminary
examination of the test scores of 124 twins with a history of reading difficulties and 154 twins with no history of reading
difficulties indicates that over the 5- to 6-year interval between assessments, cognitive and reading performance are highly
stable. As a group, those subjects with a history of reading difficulties had substantial deficits relative to control subjects
on all measures at initial assessment, and significant deficits remained at follow-up. The stability noted for all cognitive
and achievement measures was highest for a composite measure of reading, whose average stability correlation across groups
was 0.80. Results of preliminary behavior genetic analyses for this measure indicated that shared genetic influences accounted
for 86% and 49% of the phenotypic correlations between the two assessments for twin pairs with and without reading difficulties,
respectively. In addition, genetic correlations reached unity for both groups, suggesting that the same genetic influences
are manifested at both time points. 相似文献
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肥胖发生机制的研究新进展 总被引：3，自引：0，他引：3
戴昕 《首都体育学院学报》2004,16(2):97-98
从肥胖的病因学分析角度,对肥胖的中枢机制,UCPs研究、遗传因素与肥胖、脂肪细胞凋亡与肥胖等几个方面进行了研究。 相似文献
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延迟性肌肉酸痛及其防治的某些进展(综述) 总被引：3，自引：0，他引：3
由于延迟性肌肉酸痛(DOMS)的病因、病理机制到目前为止还未完全清晰,也没有真正有效清除或减轻DOMS的方法。文章对近年来关于DOMS的病因、病理以及它的防治进展进行一个小结,指出DOMS是一个多因素、多环节共同作用的结果,针对各单个因素的治疗方法均未获得满意疗效,而通过整体治疗的中国传统医学或许是解决DOMS的有效途径之一。 相似文献
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