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1.
Linda Gilmore Monica Cuskelly Melissa Browning 《International Journal of Disability, Development & Education》2015,62(3):265-275
The main purpose of the current study was to provide empirical evidence to support or refute assumptions of phenotypic deficits in motivation for children with Down syndrome (DS). Children with moderate intellectual disability (MID) associated with etiologies other than DS were recruited in an extension of a previous study that involved children with DS and typically developing children. The participants were 29 children with MID and 33 children with DS who were matched on mental age to 33 typically developing children, aged 3–8 years. Mastery motivation was assessed on task measures of curiosity, preference for challenge and persistence, as well as parental reports. There were no significant group differences on the mastery motivation tasks. Parental ratings of mastery motivation differed, with typically developing children generally being rated more highly than each of the disability groups. The view that motivational deficits are part of the DS behavioural phenotype was not supported. 相似文献
2.
模因论反映了语言的进化规律,模因的特点是通过模仿而传播,为外语教学提供了新的视角。基因型和表现型模因应用于大学英语四六级写作教学中,体现出背诵、仿写及联想是提高大学生英语写作水平的有效途径,有助于提高英语写作教学效果,加强学生的英语写作创新能力。 相似文献
3.
Inborn errors of metabolism （IEM） include a broad spectrum of defects of various gene products that affect intermediary metabolism in the body. Studying the molecular and biochemical mechanisms of those inherited disorder, systematically summarizing the disease phenotype and natural history, providing diagnostic rationale and methodology and treatment strategy comprise the context of human biochemical genetics. This session focused on： （1） manifestations of representative metabolic disorders; （2） the emergent technology and application of newborn screening of metabolic disorders using tandem mass spectrometry; （3） principles of managing IEM; （4） the concept of carrier testing aiming prevention. Early detection of patients with IEM allows early intervention and more options for treatment. 相似文献
4.
郑莉君 《内蒙古师范大学学报(哲学社会科学版)》1996,(2)
皮亚杰把生物学的方法和表型复制理论运用于认识论研究，不仅因为生物学是发生认识论的重要基础，而且因为这样可以使皮亚杰在研究认识论时避免本体论问题。所以，生物学是发生认识论最重要的基础。 相似文献
5.
摘要：目的：通过分析Ⅴ型胶原蛋白ａ1链（COL5A1）基因多态性与60名中国北方汉族女子专业长跑运动员机能指标的关联性,探寻预测有氧耐力表型的分子标记。方法：采用联合测试法测得无氧阈和最大摄氧量相关指标,肺功仪测得肺功相关指标。用PCR-RFLP分析COL5A1基因的rs13946、rs12722多态性。结果：1）rs12722位点：不同基因型运动员之间无氧阈摄氧量、无氧阈摄氧量相对值有显著性差异（P<0.05）,TT型运动员显著大于CC和CT型。2）rs13946位点：该位点与有氧耐力表型以及肺功之间无关联（P<0.05）。3）rs13946-rs12722单体型：携带TC单体型运动员的无氧阈摄氧量和无氧阈摄氧量相对值指标均显著高于非TC单体型运动员（P<0.025）。结论：1）COL5A1 rs12722 TT基因型可作为预测中国北方汉族女子长跑运动员无氧阈强度下机体氧耗量的分子遗传学标记。2）TC单体型可作为预测北方汉族女子长跑运动员无氧阈摄氧量及其相对值指标的分子遗传学标记。 相似文献
6.
一种离散型多目标粒子群优化算法 总被引：1，自引：1，他引：0
为获得更好的非劣前端,提出一种离散型多目标粒子群优化算法。该算法根据离散型多目标优化问题的特点,将种群分成多个子种群,在各个子种群中利用表现型共享的适应度函数选择每个子种群的最优粒子。通过多个最优粒子的引导,使整个种群分布更均匀,避免陷入局部最优,保证了解的多样性。实验表明了该算法的有效性。 相似文献
7.
为了检测孵化温度是否影响孵化成功率、孵化期和孵出幼体的质量,本研究设置了4个恒定温度(21,24,28,32℃)和一个波动温度孵化中华鳖卵。孵化温度影响孵化期和多数孵出幼体的表型特征,21,24,28,32?C和波动温度的平均孵化期分别为75.9、74.9、46.0、39.4和49.4天。五个孵化温度孵出幼体的湿重、背甲宽和腹甲宽差异显著,而背甲长差异不显著,来自波动孵化温度的孵出幼体较其它温度的个体要小。温度诱导的幼体形态大小对幼体的早期生长有重要影响,体重、背甲长、背甲宽和腹甲宽在第一个越冬季前差异显著,较低温度孵出(21和24℃)的幼体比较高温度(28、32℃和波动温度)的幼体体重轻,背甲长、背甲宽和腹甲宽小。 相似文献
8.
Dra?an Butorac Ivana ?elap Sanja Ka?kov Vera Robi? Tomislav Mileti? Zlata Flegar Me?tri? Andrea Hulina Krunoslav Kuna Tihana ?ani? Grubi?i? Marija Grdi? Rajkovi? 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2014,24(2):273-280
Introduction
Postmenopausal women have higher risk of cardiovascular disease. One of the contributing factors could be reduced activity of anti-atherogenic enzyme paraoxonase 1 (PON1). The aim of this study was to examine differences in the lipid status, paraoxonase and arylesterase PON1 activities and PON1 phenotype in women with regular menstrual cycle and in postmenopausal women.Materials and methods:
The study included 51 women in reproductive age (25 in follicular and 26 in luteal phase of the menstrual cycle) and 23 women in postmenopause. Lipid parameters in sera were determined using original reagents and according to manufacturer protocol. PON1 activity in serum was assessed by spectrophotometric method with substrates: paraoxon and phenylacetate. PON1 phenotype was determined by double substrate method.Results:
Compared to the women in follicular and luteal phase, postmenopausal women have significantly higher concentration of triglyceride [0.9 (0.7–1.3), 0.7 (0.6–1.0) vs. 1.5 (0.9–1.7) mmol/L; P = 0.002], cholesterol [5.10 (4.78–6.10), 5.05 (4.70–5.40) vs. 6.30 (5.73–7.23) mmol/L; P < 0.001], LDL [3.00 (2.56–3.63), 3.00 (2.70–3.70) vs. 3.90 (3.23–4.50) mmol/L; P < 0.001], and apolipoprotein B [0.88 (0.75–1.00), 0.79 (0.68–1.00) vs. 1.07 (0.90–1.24) mmol/L; P = 0.002]. PON1 basal [104 (66–260), 106 (63–250) vs. 93 (71–165) U/L; P = 0.847] and salt-stimulated paraoxonase activity [210 (131–462), 211 (120–442) vs. 180 (139–296) U/L; P = 0.857] as well as arylesterase activity [74 (63–82), 70 (54–91) vs. 70 (60–81) kU/L; P = 0.906] and PON1 phenotype (P = 0.810) were not different in the study groups.Conclusion:
There are no differences in PON1 activity and PON1 phenotype between women with regular menstrual cycle and postmenopausal women. 相似文献9.
目的：探讨ACTN3 R577X多态性与青少年运动员爆发力素质及其表型指标的关联性,并检验ACTN3 R577X作为分子标记在青少年运动员科学选材中应用的可行性。方法：选取上海地区青少年业余体校青少年运动员96名,其中男运动员58名,女运动员38名,根据项目特点分为爆发力组和耐力组;利用SNaPshot SNP分型技术对采集的DNA样本进行基因分型。爆发力组运动员进行立定跳远、原地纵跳指标的测试。结果：青少年爆发力组运动员ACTN3 R577X基因型分布与青少年耐力组运动员(x2=7.289,P<0.05)和对照组人群(x2=6.831,P<0.05)均存在显著性差异;青少年爆发力组运动员的ACTN3 R577X等位基因频率与青少年耐力组运动员(x2=7.498,P<0.01)和对照组人群(x2=7.923,P<0.01)均存在显著性差异。在青少年爆发力组男、女运动员中,RR、RX基因型运动员的立定跳远和原地纵跳成绩都要显著性高于XX基因型的运动员（P<0.05,P<0.01）。结论 ACTN3基因 R577X多态性与上海地区青少年运动员爆发力素质存在关联,ACTN3基因 R577X多态性与立定跳远、原地纵跳等爆发力素质表型指标存在关联,ACTN3 基因R577X多态性可以作为青少年速度力量型运动员选材的分子标记。 相似文献
10.
吴央波 《宁波教育学院学报》2012,(4):59-63
利用语言模因复制和传播的特点,结合《新编大学英语》教程,探讨了模因论启示下的大学英语写作教学,并着重分析了"内容相同形式各异"的基因型语言模因和"形式相同内容各异"的表现型语言模因,认为这些模因的表现方式可以应用于大学英语写作教学。 相似文献