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1.
专利网络分析在技术路线图中的应用 总被引:3,自引:0,他引:3
简单介绍技术路线图的概念及绘制过程中存在的缺陷,提出可以将专利网络分析引入技术路线图中的想法。并在此基础上研究专利网络分析在技术路线图绘制中具体的实施办法和有可能带来的好处。最后,以美国的部分专利为例并利用分析工具Pajek作专利网络分析实施和应用的实证研究。 相似文献
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基于专利引文分析的时间线技术 总被引:3,自引:0,他引:3
在对专利引文可视化技术现状进行分析的基础上,将基于引文分析的时间线技术运用到专利文献的可视化分析。详细阐述该技术的理论依据、设计思想,并用美国专利数据库中的DVD激光头专利进行技术应用,证明该技术能揭示专利文献中的技术热点及其发展演变,并挖掘关键技术。 相似文献
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本文基于Dialog联机检索,以德温特世界专利索引数据库和专利引文索引数据库为数据源,对质子交换膜(PEM)燃料电池行业进行了专利分析研究。作者用实例说明了利用各种Dialog高级检索指令实现行业专利分析的技巧。通过分析研究,发现了PEM燃料电池行业的领先企业、技术领军人物、产业发展前景、全球技术/市场布局、关键技术、研发热点等。研究表明,Dialog?联机检索在行业专利分析中是一种有效的工具。 相似文献
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BackgroundPlanctomycetes is a phylum of biofilm-forming bacteria with numerous biosynthetic gene clusters, offering a promising source of new bioactive secondary metabolites. However, the current generation of chemically defined media achieves only low biomass yields, hindering research on these species. We therefore developed a chemically defined medium for the model organism Planctopirus limnophila to increase biomass production.ResultsWe found that P. limnophila grows best with a 10 mM sodium phosphate buffer. The replacement of complex nitrogen sources with defined amino acid solutions did not inhibit growth. Screening for vitamin requirements revealed that only cyanocobalamin (B12) is needed for growth. We used response surface methodology to optimize the medium, resulting in concentrations of 10 g/L glucose, 34 mL/L Hutner’s basal salts, 23.18 mM KNO3, 2.318 mM NH4Cl and 0.02 mg/L cyanocobalamin. The analysis of amino acid consumption allowed us to develop a customized amino acid solution lacking six of the amino acids present in Aminoplasmal 10%. Fed-batch cultivation in a bioreactor using the optimized medium achieved a final ΔOD600 of 46.8 ± 0.5 after 108 h, corresponding to a cell dry weight of 13.6 ± 0.7 g/L.ConclusionsThe optimized chemically defined medium allowed us to produce larger amounts of biomass more quickly than reported in earlier studies. Further research should focus on triggering P. limnophila biofilm formation to activate the gene clusters responsible for secondary metabolism.How to cite: Kruppa OC, Gerlach D, Fan R, et al. Development of a chemically defined medium for Planctopirus limnophila to increase biomass production. Electron J Biotechnol 2021;54. https://doi.org/10.1016/j.ejbt.2021.09.002. 相似文献
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摘要:目的:通过对我国优秀沙滩排球运动员薛晨肩关节脱臼术案例进行分析,探索优秀运动员备战奥运会期间从手术后到重返训练场间的身体运动功能康复训练安排。方法:借鉴重返赛场训练的方法手段,从康复医学、体能训练和运动表现等多学科角度设计有针对性的康复训练方法。通过对比训练前后关节活动度、肌肉力量、功能动作筛查结果以及下肢力量爆发力测试结果检验以优秀沙滩排球运动员肩关节脱臼为个案分析重返赛场的可行性训练策略。结果:通过10周身体运动功能训练,运动员下肢爆发力、损伤侧肩关节内外旋活动度、均有所增加。功能动作筛查分数降低。但损伤侧肩关节内旋肌力、腹侧核心耐力有所下降。结论:以优秀沙滩排球运动员肩关节脱臼重返赛场的训练策略为个案分析,探索从运动损伤术后至重返赛场训练过程的周期安排、训练方法的有效性;通过科学整合康复训练、体能训练和专项技术训练不同训练内容,循序渐进的帮助运动员恢复专项技术和运动能力。 相似文献
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Moataz Eltoukhy Adam Kelly Chang-Young Kim Hyung-Pil Jun Richard Campbell 《Sports biomechanics / International Society of Biomechanics in Sports》2016,15(1):89-102
Cost effective, quantifiable assessment of lower extremity movement represents potential improvement over standard tools for evaluation of injury risk. Ten healthy participants completed three trials of a drop jump, overhead squat, and single leg squat task. Peak hip and knee kinematics were assessed using an 8 camera BTS Smart 7000DX motion analysis system and the Microsoft Kinect® camera system. The agreement and consistency between both uncorrected and correct Kinect kinematic variables and the BTS camera system were assessed using interclass correlations coefficients. Peak sagittal plane kinematics measured using the Microsoft Kinect® camera system explained a significant amount of variance [Rangehip = 43.5–62.8%; Rangeknee = 67.5–89.6%] in peak kinematics measured using the BTS camera system. Across tasks, peak knee flexion angle and peak hip flexion were found to be consistent and in agreement when the Microsoft Kinect® camera system was directly compared to the BTS camera system but these values were improved following application of a corrective factor. The Microsoft Kinect® may not be an appropriate surrogate for traditional motion analysis technology, but it may have potential applications as a real-time feedback tool in pathological or high injury risk populations. 相似文献
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Developing local oral reading fluency cut scores for predicting high‐stakes test performance 下载免费PDF全文
Sally L. Grapin John H. Kranzler Nancy Waldron Diana Joyce‐Beaulieu James Algina 《Psychology in the schools》2017,54(9):932-946
This study evaluated the classification accuracy of a second grade oral reading fluency curriculum‐based measure (R‐CBM) in predicting third grade state test performance. It also compared the long‐term classification accuracy of local and publisher‐recommended R‐CBM cut scores. Participants were 266 students who were divided into a calibration sample (n = 170) and two cross‐validation samples (n = 46; n = 50), respectively. Using calibration sample data, local fall, winter, and spring R‐CBM cut scores for predicting students’ state test performance were developed using three methods: discriminant analysis (DA), logistic regression (LR), and receiver operating characteristic curve analysis (ROC). The classification accuracy of local and publisher‐recommended cut scores was evaluated across subsamples. Only DA and ROC produced cut scores that maintained adequate sensitivity (≥.70) across cohorts; however, LR and publisher‐recommended scores had higher levels of specificity and overall correct classification. Implications for developing local cut scores are discussed. 相似文献
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通过对高能量药物筛选基本过程的分析 ,探索了靶分子固定化可能对筛选质量构成的影响 .从分子相互作用看 ,实际的过程远较理想的情况复杂 .分子间存在的静电力、疏水作用力及氢键力能对固定化的机理构成较大影响 ,甚至可能诱发多层吸附的固定化模式 .基于固定化过程中可能存在的靶分子与靶分子、靶分子与微球、体相与表面相之间的相互作用 ,构筑了相应的数学物理模型 ,为实际的筛选工作提供了可参考的理论依据 . 相似文献