Novel Mechanism Idientii ed for Establishment of Kaposi's SarcomaAssociated Herpesvirus Latency     

《中国科学院院刊(英文版)》2014,(3)

<正>On April 17,Journal of Virology published an article online entitled"Kaposi’s Sarcoma-Associated Herpesvirus-Encoded LANA Interacts with Host KAP1 to Facilitate Establishment of Viral Latency"by Prof.LAN Ke’s lab at the Institut Pasteur of Shanghai,Chinese Academy of Sciences.This article was also selected as a spotlight article of signifi cant interest by the editors.Kaposi’s sarcoma-associated herpesvirus(KSHV)typically displays two different phases in its life cycle,including the default latent phase as well as the lytic phase.This virus could establish a latent infection in a very short time(typically 24~48 hours)since its invasion into the host cell and stay there for the lifetime of the latter.The latent infection is the precondition of its pathogenesis and  相似文献