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以易制备的2-(1,2-亚乙/1,3-亚丙二硫)亚甲基-3-羰基丁酸1为原料,经与氯化亚砜的氯化反应后,与胺反应成功地以较好产率(40.5%-72.0%)合成重要的有机合成中间体2-(1,2-亚乙/1,3一亚丙二硫)亚甲基-3-羰基-N-芳(烷)基丁酰胺3. 相似文献
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本文综述了邻二甲酰胺类化合物和邻甲酰氨基苯甲酰胺类化合物就其苯环变换为芳杂环的化合物及其活性,并且展望了双酰胺类化合物的研究趋势。 相似文献
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INTRODUCTION Amides are important commercial and biologi-cal compounds. Because amides constitute the backbone of protein molecules, their chemistry is of extreme importance. The penicillin and cephalosporin antibiotics are among the best-known products of the pharmaceutical industry. For this reason, the devel-opment of new and simple methods for the synthesis of the peptide bond always constitute an important addition to the field of natural products synthesis. Several general methods … 相似文献
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