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本文综述了新生反刍动物产后期营养代谢、内分泌和免疫功能特点和发育变化,为进一步深入了解和揭示这些变化特点提供了参考资料,并为改善饲养管理、防御新生期疾病提供了理论依据. 相似文献
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This study examined the effects of equal anaerobic and aerobic total work outputs on the relationship between reproductive hormones in men. Nine subjects performed three randomized trials on separate days: (1) 1 h period of rest (control), (2) 1 h continuous aerobic exercise (65% VO2 max), and (3) 1 h intermittent anaerobic exercise (which included 2 min exercise periods at 110% FO2 max). The total work output of the aerobic and anaerobic trials were equated. For the 8 h after each experimental trial, blood samples were collected hourly and analysed for testosterone, luteinizing hormone (LH), follicle‐stimulating hormone (FSH), prolactin and cortisol. Diet, physical activity and circadian influences were all controlled. Compared with the control, the aerobic and anaerobic trials significantly (P < 0.05) elevated testosterone, prolactin and cortisol; however, these changes were transient and returned to control levels within 1–2 h of recovery. Neither exercise produced significant (P > 0.05) changes from control for LH and FSH. The area under the hormonal response curves (AUC) was calculated for the 8‐h recovery period. The testosterone and LH AUC results did not differ (P > 0.05) among the trials (the FSH AUC was not calculated). The prolactin AUC for the aerobic and anaerobic trials were greater (P < 0.01) than the control trial. The cortisol AUC for the anaerobic trial was greater than both the control and aerobic trials (P < 0.05), but the aerobic and control trials did not differ from one another. Correlation analysis among the AUC results within each trial showed testosterone and LH to be significantly related during the control (r = 0.723, P < 0.05) and aerobic (r = 0.801, P < 0.01) trials, but not so during the anaerobic trial (r = 0.430, P > 0.05). No other significant correlations were found. The present findings suggest the relationship between testosterone and LH is affected by anaerobic exercise but not aerobic exercise. However, the effect of anaerobic exercise upon the testosterone‐LH relationship did not seem related to the concurrently induced prolactin or cortisol changes. Anaerobic exercise may produce some degree of temporary alteration within the testosterone‐LH component of the hypothalamic‐pituitary‐gonadal axis; however, the mechanism for this phenomenon remains unclear. 相似文献
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大豆黄酮对大鼠肌肉生长、内分泌水平的影响 总被引：5，自引：0，他引：5
目的 :本文主要研究大豆黄酮对雄性大鼠肌肉生长、内分泌水平的影响。方法 :大豆黄酮溶解于花生油中 ,将大鼠随机分为三组 ,分别灌服大豆黄酮 5 0mg/kg、大豆黄酮 10 0mg/kg、花生油。四周后对大鼠眼窝静脉丛采血 ,颈椎脱臼处死。离心分离血清测定睾酮、生长激素含量 ;腓肠肌称重、腓肠肌纤维及脂肪细胞测定。结果表明 :与对照组相比 ,5 0mg/kg大豆黄酮组睾酮提高 2 3 .89% (p <0 .0 5 )、生长激素提高 15 .0 7% (p <0 .0 5 )。 10 0mg/kg大豆黄酮组睾酮含量下降5 1.2 5 % (p <0 .0 1) ,生长激素下降 13 .3 8% (p <0 .0 5 )。腓肠肌体重比 5 0mg/kg大豆黄酮组与对照组相比有显组性意义 ,10 0mg/kg大豆黄酮组无显著性意义。 5 0mg/kg大豆黄酮组腓肠肌肌纤维直径大小提高 14 .49% (p <0 .0 5 ) ,肌密度上升 1.2 1% (p >0 .0 5 )脂肪细胞直径大小下降 8.78% (p >0 .0 5 ) ,脂肪细胞密度上升 5 .45 % (p >0 .0 5 )。 10 0mg/kg大豆黄酮组与对照组大鼠相比 ,肌纤维直径大小下降 10 .74% (p >0 .0 5 ) ,肌密度上升 2 .43 % (p >0 .0 5 ) ,脂肪细胞直径大小下降 4.88% (p >0 .0 5 ) ,脂肪细胞密度上升 3 .64 % (p >0 .0 5 )。结论 :大豆黄酮对大鼠肌肉生长和内分泌变化具有调节作用 ,但此调节作用与使用的剂量 相似文献
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Vibha Uppal Chittranjan Vij Gurdeep Kaur Bedi Anil Vij Basu Dev Banerjee 《Indian journal of clinical biochemistry : IJCB》2013,28(4):336-341
The study was planned to assess the prevalence of thyroid disorders in type 2 diabetes in North Indian population and to correlate the serum insulin and glycosylated haemoglobin levels with thyroid hormones. It is a case control study. One hundred and twenty patients of type 2 diabetes were included in the study along with 117 adults of the same age group and normal glucose levels as controls. All blood samples were taken from subjects who fasted for at least 12 h before the blood collection. Glycosylated hemoglobin was determined by ion exchange chromatography and serum insulin and thyroid hormones were assessed through enzyme linked immunosorbent assay. Fasting blood glucose and glycosylated haemoglobin levels were significantly higher in diabetics showing a poor glucose control. Serum tri-iodothyronine values were significantly lower in diabetics. There was a significant correlation between glycosylated haemoglobin and thyroid hormones. There was no correlation between serum insulin and thyroid hormones. 相似文献
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Moushumi Lodh Rajarshi Mukhopadhyay 《Indian journal of clinical biochemistry : IJCB》2016,31(1):121-124
We present three cases who presented to our Endocrinology OPD a few days apart with the common complaints of no or minimal development of secondary sexual characteristics. Although they had similar problems, investigations revealed a spectrum of different clinical, biochemical and genetic abnormalities. All the patients had otherwise normal anterior pituitary hormone secretion and sellar anatomy. One had a short Y chromosome, one was a Klinefelter syndrome and the other had no chromosomal abnormality. These findings along with absence of any detectable abnormality on pituitary imaging helped us diagnose these cases as Idiopathic hypogonadotropic hypogonadism. Treatment with testosterone showed marked improvement at 1 year follow up. 相似文献
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Exercise is a potent stimulus for the release of human growth hormone (hGH), but the time course of the hGH response to sprint exercise has not been studied. The aim of the present study was to determine the time course of the hGH response to a 6 s and a 30 s maximal sprint on a cycle ergometer. Nine males completed two trials, on one occasion performing a single 6 s sprint and on another a single 30 s sprint. They then rested on a couch for 4 h while blood samples were obtained. Three of the participants completed a further control trial involving no exercise. Metabolic responses were greater after the 30 s sprint than after the 6 s sprint. The highest measured mean serum hGH concentrations after the 30 s sprint were more than 450% greater than after the 6 s sprint (18.5 - 3.1 vs 4.0 - 1.5 w g·l -1 , P ? 0.05). Serum hGH also remained elevated for 90-120 min after the 30 s sprint compared with ~ 60 min after the 6 s sprint. There was a large inter-individual variation in the hGH response to the 30 s sprint. In the control trial, serum hGH concentrations were not elevated above baseline at any time. It would appear that the duration of a bout of maximal sprint exercise determines the magnitude of the hGH response, although the mechanism for this is still unclear. 相似文献
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