Changes in serum haptoglobin as an acute response to a marathon road race     

Linda M. Egan  Phillip B. Watts  Barbara C. Silta 《Journal of sports sciences》2013,31(1):55-60

In order to assess the possible occurrence of acute haemolysis with prolonged exertion, serum haptoglobin levels were determined from venous blood samples collected from eight male runners immediately preceding (PreRH), immediately following (PRH1), and 6 h following (PRH2) completion of a marathon road race. The subjects’ mean age, percentage of body fat, and maximum oxygen uptake (VO₂max) were 46 ± 9 years, 12.1 ± 3.4% and 54.9 ± 8.4 ml kg^‐1 min^‐1, respectively. The mean race finish time for the subjects was 3:35 ± O: 18 h:min. The PreRH, PRH1 and PRH2 averaged 129 ± 18, 97 ± 48 and 86 ± 35 mg dl^‐1 respectively. Significant differences of –32.5 mg dl^‐1 between PreRH versus PRH1 and –42.5 mg dl^‐1 between PreRH versus PRH2 were found. The difference between PRH1 and PRH2 of –10.6 mg dl^‐1 was not significant. No significant correlations were found between the decreases in serum haptoglobin and VO₂max or race finish time. The data suggest the occurrence of an acute haemolysis with performance of the marathon road race.  相似文献