递增负荷运动过程中ER、PR水平的变化及其与性腺类固醇的关系   总被引：2，自引：0，他引：2  

郑陆  隋波  潘力平  李晔  沈东颖  王娟  林晓光  王明燕  段平 《山东体育学院学报》2005,21(5):54-57,61

低性腺类固醇水平是AMi的重要特征之一.为了探讨低性激素环境下ER（雌激素受体）、PR（孕激素受体）的变化特点及激素与受体间的相互影响作用关系，并探讨其在运动性月经失调中的作用机制，本研究对递增负荷运动过程中及4个恢复期后，大鼠子宫和卵巢ER、PR及血清E2、P水平的变化进行了连续监测.结果显示，血清E2、P随运动负荷量的加大而逐渐降低，组织ER、PR水平随运动负荷量的加大呈渐进性升高.受体水平在停训后的恢复期内随着E2、P水平的回升，逐渐回落.结果表明，运动中受体水平的变化可能为非激素依赖性升高，这种升高或许是机体对长期运动训练造成的低性激素环境的一种适应性反应，可能是AMI病理机制过程的重要一环.恢复期受体水平的恢复与E2水平的升高具有直接关系。  相似文献   

补充三宝胶囊对大运动量训练大鼠血清性激素水平与运动能力的影响     

卢向阳  乔玉成  张红娟 《北京体育大学学报》2006,29(4):497-499

为了探讨三宝胶囊对大运动量训练大鼠血清睾酮(T)、皮质酮(Cort)、黄体生成素(LH)含量及运动能力的影响.将雄性SD大鼠37只,随机分为:安静对照组(C);中药对照组(M);运动组(T);中药运动组(M T).中药组和中药运动组分别灌服三宝胶囊,运动组与中药运动组进行8周大运动量训练.于第7周末进行力竭性运动实验,第8周末次训练后18 h取样测定血清睾酮、皮质酮、黄体生成素含量.结果发现:1)服用三宝胶囊的中药运动组大鼠游泳至力竭的时间比单纯运动组延长了38.12%(P＜0.01).2)大运动量训练后18 h,T组大鼠血清睾酮仍处于较低水平(P＜0.01);M T组血清睾酮水平显著上升(P＜0.05).3)T组血清Cort水平显著增高(P＜0.05),M T组有降低趋势,但无统计学意义.4)T组T/Cort比值明显下降(P＜0.01),M T组T/Cort比值明显增高(P＜0.01).5)T组血清LH明显升高(P＜0.05),M T组LH基本维持在正常水平.表明:大运动量训练机体长时期服用三宝胶囊能促使血睾酮水平的提高,防止因大运动量训练导致的睾酮/皮质酮比值下降,有助于延缓大运动量训练疲劳的产生,促进恢复,提高运动能力.  相似文献   

Study on pig growth hormone gene polymorphisms in western meat-type breeds and Chinese local breeds     

宋成义  高波  经荣斌  陶勇  毛九德 《浙江大学学报(A卷英文版)》2003,4(6):734-739

Chinese Meishan and Jiangquhai pigs are two of the most prolific pigs in the world, but their growth rate is lower than that of Duroc, Landrace and Pietrain pigs. It is suggested that growth rate is regulated by growth hormone. The objective of the current study was to analyze the porcine growth hormone (pGH) gene polymorphisms based on the polymerase chain reaction restriction fragment-length polymorphism method (PCR-RFLP) for three western meat-type breeds (Duroc, Landrace and Pietrain) and two local Chinese pigs (Meishan and Jiangquhai). Five polymorphic restriction sites were detected with the ApaI, MspI, BspI and HhaI restriction enzymes in two amplified fragments (605 bp, -119 to +486; 506 bp, +206 to +711). Breed difference was found only in the 506 bp fragment. There was no difference in allelic frequencies of BspI and HhaI restriction sites among the five breeds (P>0.05). Landrace and Meishan pigs lacked allele G3 of MspI site. The allele G3 frequency of restriction MspI site of the 506 bp fragment in Pietrain pigs was higher than that in Duroc and Jianquhai pigs (P<0.001). For ApaI site, the Meishan pigs lacked allele G1; no difference was found in allelic frequencies among Pietrain, Duroc, Landrace and Jiangquhai pigs (P>0.05). This new and rapid PCR-RFLP typing method is an attractive tool for analysis of porcine growth hormone gene restriction sites. The differences in MspI and ApaI restriction sites may explain the growth difference between the foreign meat-type breeds above mentioned and local Chinese pigs.  相似文献   

环境激素的种类与危害     

詹秀环  王子云 《周口师范学院学报》2003,20(2):56-59

20世纪后期，野生动物和人类的内分泌系统、免疫系统、神经系统出现了各种各样的奇异现象，重要的原因是环境激素污染．阐述了环境激素的概念、来源、种类、危害及自我保护对策．  相似文献   

豆瓣绿的水培繁殖试验研究   总被引：4，自引：0，他引：4  

赵兰枝  刘振威  陈进洁  张允伟 《河南科技学院学报》2006,34(3):35-37

采用不同浓度的激素和不同浓度的营养液对豆瓣绿进行水培生根研究。结果表明：用不同浓度的营养液处理豆瓣绿，以1／2营养液生根效果最好，达13．3条，根鲜重达0．093g／棵，清水次之；用不同浓度的生长激素处理豆瓣绿，以30mg／L浓度的3-IBA生根效果最好，生根数达16．5条，根鲜重达0．132g／棵，10mg／L次之；在营养液与激素的互作处理中，清水与30mg／L激素、全营养与10mg／L激素的互作处理分别对豆瓣绿的生根数与根鲜重表现较优。  相似文献   

Parathyroid and Calcium Status in Patients with Thalassemia     

Goyal M  Abrol P  Lal H 《Indian journal of clinical biochemistry : IJCB》2010,25(4):385-387

Thirty patients with thalassemia major receiving repeated blood transfusion were studied to see their serum parathyroid hormone (PTH) and calcium status. Serum PTH, serum and 24 h urinary calcium, and serum alkaline phosphatase, phosphorus, and albumin-corrected calcium levels were determined. Half of these patients, in addition to transfusion, were also supplemented with vitamin D (60,000 IU for 10d) and calcium (1500 mg/day for 3 months). Serum PTH, and serum and 24 h urinary calcium concentrations of the patients receiving transfusions were found to be significantly reduced while their serum alkaline phosphatase, phosphorus, and albumin-corrected calcium levels were not significantly altered when compared to the respective mean values for the control group. Vitamin D and calcium supplementation significantly increased their serum PTH and calcium levels. Supplementations also increased urinary excretion of calcium. The results thus suggest that patients with thalassemia have hypoparathyroidism and reduced serum calcium concentrations that in turn were improved with vitamin D and calcium supplementation.  相似文献   

试论中老年人股骨颈骨折的防治与体育康复     

江孝珠 《体育科学研究》1998,2(4):47-50

中老年人应及早防治“骨质疏松症”。通过加强自我防治意识;及时补充微量元素和食用含钙量高的食物。坚持体育运动,提高钙的利用率以防患于未然。一旦发生股骨颈骨折,应采用中,西医结合,服用药物与体育医疗相结合,使其早日康复,达到“老能自养”,“老有所乐”。  相似文献   

青少年生长激素分泌水平的研究进展     

张娟  周军 《首都体育学院学报》2007,19(3):47-49

生长激素是控制人体生长发育最重要的激素。生长激素缺乏是导致青 少年身材矮小的主要原因之一。就近年来国内外有关青少年生长激素水平的研究 进展进行综述,探讨青少年生长激素分泌变化的一般规律及其影响因素,指出生长 激素在生理条件下,主要受睡眠、药物、运动等因素的影响,并针对影响因素的改 变而增加青少年生长激素分泌这一问题进行分析,提出运动是一种理想的调节身 体GH分泌的手段。另外,许多文献均指出运动强度、运动时间、运动方式等诸方 面,对GH的分泌有影响,但对此均无统一明确的论断,有待于进一步研究。并且针 对不同的年龄、不同的性别、不同的体质等,如何综合运用这些运动手段来调节 GH的分泌、促进身体生长,也是我们应该深入探讨的课题。  相似文献   

Effect of epidermal growth factor on follicle-stimulating hormone-induced proliferation of granulosa cells from chicken prehierarchical follicles     

Lin JX  Jia YD  Zhang CQ 《Journal of Zhejiang University. Science. B》2011,12(11):875-883

The development of ovarian follicular cells is controlled by multiple circulating and local hormones and factors, including follicle-stimulating hormone (FSH) and epidermal growth factor (EGF). In this study, the stage-specific effect of EGF on FSH-induced proliferation of granulosa cells was evaluated in the ovarian follicles of egg-laying chickens. Results showed that EGF and its receptor (EGFR) mRNAs displayed a high expression in granulosa cells from the prehierarchical follicles, including the large white follicle (LWF) and small yellow follicle (SYF), and thereafter the expression decreased markedly to the stage of the largest preovulatory follicle. SYF represents a turning point of EGF/EGFR mRNA expression during follicle selection. Subsequently the granulosa cells from SYF were cultured to reveal the mediation of EGF in FSH action. Cell proliferation was remarkably increased by treatment with either EGF or FSH (0.1–100 ng/ml). This result was confirmed by elevated proliferating cell nuclear antigen (PCNA) expression and decreased cell apoptosis. Furthermore, EGF-induced cell proliferation was accompanied by increased mRNA expressions of EGFR, FSH receptor, and the cell cycle-regulating genes (cyclins D1 and E1, cyclin-dependent kinases 2 and 6) as well as decreased expression of luteinizing hormone receptor mRNA. However, the EGF or FSH-elicited effect was reversed by simultaneous treatment with an EGFR inhibitor AG1478. In conclusion, EGF and EGFR expressions manifested stage-specific changes during follicular development and EGF mediated FSH-induced cell proliferation and retarded cell differentiation in the prehierarchical follicles. These expressions thus stimulated follicular growth before selection in the egg-laying chicken.  相似文献   

调节激素刺激对超负荷运动致骨骼坏死的治疗作用     

高红梅 《科技通报》2014,(12)

目的:探讨超负荷运动骨折致骨骼坏死患者的临床特点及调节激素生长刺激治疗方案。方法:分析2013年9月~2014年1月收治31例超负荷运动骨折致骨骼坏死患者的临床资料,总结超负荷运动骨折致骨骼坏死患者的临床特点及调节激素生长刺激治疗方案。结果:31例患者骨骼坏死后早期表现为骨骼受伤部位不适、神经疼痛等,逐渐出现意识变差、神经系统压迫性受损的表现,予早期骨骼固定、骨骼按摩、骨骼触感恢复及骨骼神经恢复等治疗,通过激素生长刺激作用,调节激素对于人体的刺激,使得坏死骨骼生长,31例患者住院1~40 d,11例好转,13例骨骼坏死部分恢复,2例骨骼坏死全部恢复。结论:超负荷运动骨折致骨骼坏死有很强的破坏性,临床表现为骨骼和相关神经衰竭,恢复率低,目前暂无特效调节激素生长刺激治疗方案,及早采取积极的治疗措施:如早期多次骨骼触感恢复或加骨骼神经恢复、大剂量激素的应用对骨骼坏死的救治和改善有重大作用。  相似文献