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1.
Casikar V Mujica E Mongelli M Aliaga J Lopez N Smith C Bartholomew F 《Indian journal of clinical biochemistry : IJCB》2010,25(3):311-314
Andean Indians have used coca leaves (Erythroxylon coca and related species) for centuries to enhance physical performance. The benefits and disadvantages of using coca leaf have
been a subject of many political debates. The aim of this study was to investigate the effects of chewing coca leaves on biochemical
and physiological parameters. Cutaneous microdialysis catheters were used to estimate systemic biochemical changes. We subjected
10 healthy adult males (local residents) in Cajamarca (Peru, altitude 2700 m) to a standardised exercise routine on a stationary
cycle ergometer. The blood pressure, oxygen saturation (digital), pulse, VO2 max and ECG (Holter monitor) were recorded before
the exercise. Cutaneous microdialysis catheters were introduced in the forearm. The subjects were given to chew 8 g of coca
leaves with a small amount of lime. They were then placed on the cycle ergometer for 20 min. Blood pressure, oxygen saturation,
pulse, ECG and VO2 max were recorded. Pyruvate, glucose, lactate, glycerol and glutamate levels were estimated. Oxygen saturation,
blood pressure, and pulse rate did not show any significant changes between the two groups. Glucose levels showed hyperglycaemic
response. Glycerol, Lactate and Pyruvate increased. Glutamate remained unchanged. Similar changes were not seen in the controls.
These results suggest that coca leaves have blocked the glycolytic pathway of glucose oxidation resulting in accumulation
of glucose and pyruvate. The energy requirement for exercise is being met with beta-oxidation of fatty acids. The glycerol
released was also getting accumulated since its pathway for oxidation was blocked. These experimental findings suggest that
chewing coca leaves is beneficial during exercise and that the effects are felt over a prolonged period of sustained physical
activity. 相似文献
2.
于2006年1月至2006年12月期间测定了采自浙江灵昆岛潮滩的橄榄蚶含水量、肥满度和生化成分,分析其周年变化．结果显示：橄榄蚶含水量、肥满度和各生化成分的月间变化差异显著．含水量和肥满度的周年变化范围为74．59％-81．36％和6．92％-14．11％,橄榄蚶肥满度与含水量的周年变化呈显著的负相关;软体部干物质中蛋白质、脂肪、可溶性糖、总糖和灰分的周年变化范围分别为55．17％-66．80％、5．60％-16．81％、2．43％-6．42％、6．82％-21．20％和4.37％-12．13％,不同生理变化阶段的生化成分主要与繁殖周期有关． 相似文献
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观察有氧运动对糖尿病模型大鼠血糖等生化指标的影响。四氧嘧啶诱导的糖尿病大鼠20只,随机分为实验组（10只）和对照组（10只）。实验组动物进行45d连续跑台运动,第46d断头取血测血糖、转氨酶、尿素氮和血常规指标。结果发现：有氧运动对糖尿病大鼠的BUN、MCV、MCH、MCHC无显著性（p〉0.05）影响;但与对照组相比,血糖、GPT、RBC、HCT、HGB、RDW、PLT、WBC却发生了显著性（p〈0.05）变化。 相似文献
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从案例教学法的概念与特点、生化技术案例教学组织过程及实施效果等方面着手,认为案例教学法在生化技术课程教学中培养和提高了学生工程实践能力,既掌握技术原理和方法等基本知识点,又学会了融会贯通,从而真正达到学以致用的目的． 相似文献
7.
Mukhopadhyay M Sinha R Pal M Bhattacharyya S Dan A Roy MM 《Indian journal of clinical biochemistry : IJCB》2011,26(3):274-278
The progress of fracture union requires close monitoring. Whereas, clinical examination and radiographic studies assess the
outcome, biochemical markers like serum alkaline phosphatase and urinary hydroxyproline reflect the actual status of bone
resorption and bone formation over a short time frame. 36 patients of long bone fracture were randomly allocated for the study.
When the patient reported to the Department of Orthopedics after fracture, serum and urinary samples were collected and X-ray
of the affected part were taken. Subsequent samples were collected and X-ray taken just after management (either operative
or conservative), after 3rd, 5th, 8th and 12th week, respectively after onset of fracture. According to the course of callus
formation the patients were divided into two groups that progressed to proper union or malunion. The levels of serum alkaline
phosphatase, urinary total and free hydroxyproline levels were measured and statistically analysed and compared. A statistically
significant positive correlation between total urinary hydroxyproline excretion and serum alkaline phosphatase indicate progress
towards satisfactory union. Thus, serial monitoring of biochemical markers of bone turnover can be used as an adjunct to clinical
and radiological evidence of fracture healing. 相似文献
8.
Subir Kumar Das Prasunpriya Nayak D. M. Vasudevan 《Indian journal of clinical biochemistry : IJCB》2003,18(2):111-118
A variety of laboratory tests are available to assist in the diagnosis of alcohol consumption and related disorders. The levels
of intake at which laboratory results become abnormal vary from person to person. Laboratory tests are particularly useful
in settings where cooperativeness is suspected or when a history is not available. Several biochemical and hematological tests,
such as γ-glutamyltransferase (GGT) activity, aspartate aminotransferase (AST) activity, high-density lipoprotein cholesterol
(HDL-C) content of serum, and erythrocyte mean corpuscular volume (MCV) are established markers of alcohol intake. Their validity
as markers is based largely on correlations with recent intake at a single time point and on decreases in elevated values
when heavy drinkers abstain from alcohol. These readily available laboratory tests provide important prognostic information
and should be integral part of the assessment of persons with hazardous alcohol consumption. There are several other markers
with considerable potential for more accurate reflection of recent alcohol intake. These include carbohydrate deficient transferrin,
β-hexosaminidase, acetaldehyde adducts and the urinary ratio of serotonin metabolites, 5-hydroxytryptophol and 5-hydroxyindoleacetic
acid. These markers provide hope for more sensitive and specific aids to diagnosis and improved monitoring for intake. 相似文献
9.
Biochemical changes of natural actomyosin from fresh pale, soft, exudative (PSE) and normal pork were studied, and the effects of different storage temperatures and different incubation temperature and times on sample superprecipitation, total sulfhydryl (-SH) content, and ATP (adenosine triphosphate) sensitivity were investigated. The results demonstrated that ATPase activity and thermal stability of PSE actomyosin were lower than those of normal pork; and that PSE actomyosin had higher -SH content than that of normal pork at all incubation temperatures and times tested. 相似文献
10.
古典跤属于按体重分级别双人交手对抗项目。赛前科学降控体重是比赛能否取得优异成绩的关键因素之一。对山西省古典式优秀摔跤运动员进行降体重监控的研究,以人体成分、生化指标来监控降重过程,给教练员提供科学调控赛前训练负荷,合理运用营养补剂,促进运动员机能恢复提供客观依据,以减小降体重的风险。 相似文献