Glycosylated haemoglobin and serum proteins in diabetics |
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| Authors: | Kiran Saxena N B Vasavada Ravi Saxena |
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| Institution: | 1. Department of Biochemistry, Government Medical College, 395 001, Surat (Gujart)
3. Department of Physiology, Government Medical College, 395 001, Surat (Gujarat)
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| Abstract: | The glycosylated haemoglobin was measured in two different categories of diabetic subjects. In poorly controlled subjects
of group II, a significant alteration in serum proteins was observed. Total protein along with albumin concentrations were
decreased and α2 globulin fraction was increased. Insulin therapy resulted in normalisation of blood glucose and gradual decrease in glycosylated
haemoglobin in the therapy period of eight weeks. This also resulted in a rise of total protein and albumin concentrations
with a decrease in α2 fraction. The present study indicates that prolonged therapy of insulin is needed to correct the serum protein abnormalities
in diabetics. |
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