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Diurnal variations and 24 hr. urinary excretion of mucoprotein and Tamm-Horsfall protein in renal stone patients
Authors:P P Singh  A K Pendse  Rajkiran  Bhupesh Partani
Institution:1. Department of Biochemistry, RNT Medical College, 313001, Udaipur, India
Abstract:Six consecutive day and night urine samples from 25 renal stone patients and 25 comparabe controls were collected and analysed for total mucoproteins, Tamm-Horsfall mucoprotein, & creatinine. In normal subjects the 24 hour, day and night urinary excretion of mucoprotein was 101.4±34.5, 58.2±20.1 and 40.5±19.3 mg respectively. The Tamm-Horsfall mucoprotein excretion was 43.9±18.4, 21.5±8.6 and 20.6±9.9 mg in respective samples. Stone formers excreted significantly higher amount of mucoprotein but not the Tamm-Horsfall mucoprotein. Furthermore, the diurnal variations was visible only for in case of total mucoprotein in both the groups.
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