| 老年高血压病左室肥厚与神经体液因素及室性早搏的相关性 |
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| 引用本文： | 郭航远,鲁端,王建安,何红,张湘兰,周斌全,蒋晨阳.老年高血压病左室肥厚与神经体液因素及室性早搏的相关性[J].科技通报,2001,17(1):63-66. |
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| 作者姓名： | 郭航远 鲁端 王建安 何红 张湘兰 周斌全 蒋晨阳 |
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| 作者单位： | 浙江大学医学院附属邵逸夫医院, |
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| 摘 要： | 为探讨老年高血压病左室肥厚（LVH）与部分神经体液因素之间的关系及与室性早搏，心肌缺血的相关性，老年高血压病伴左室肥厚60例为A组，单纯老年高;血压病60例为B组，对比观察心率变异，肾素（Ren)，血管紧张素（AT－II），醛固酮（Ald)，胰岛素峰值（Ins),24h动态心电图和血压等指标，结果显示：1）A组病人交感神经张力明显增高，迷走神经活性下降不明显，室性早搏的发生与交感神经张力增高有关；室性早搏与心肌缺血具有相关性；2）A组病人与Ald及Ins水平有关，与Ren和AT－II无明显相关；3）A组病人与室性早搏和心肌缺血明显相关，结论表明，老年高血压病在室肥厚患者交感神经张力增高，Ald及Ins水平升高，与室性早搏，心肌缺血具有正相关。
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| 关 键 词： | 高血压 老年 左室肥厚 神经体液 室性早搏 心肌缺血 交感神经张力 迷走神经活性 相关性 |
| 文章编号： | 1001-7119(2001)01-0063-04 |
| 修稿时间： | 2000年3月13日 |
The Relation between Hypertensive Left Ventricular Hypertrophy in the Elderly with Neurohormonal Factors and Ventricular Arrhythmias |
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| GUO Hang-yuan,LU Duan,WANG Jian-an,HE Hong,ZHANG Xiang-lanC,ZHOU Bin-quan,JIANG Chen-yang.The Relation between Hypertensive Left Ventricular Hypertrophy in the Elderly with Neurohormonal Factors and Ventricular Arrhythmias[J].Bulletin of Science and Technology,2001,17(1):63-66. |
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| Authors: | GUO Hang-yuan LU Duan WANG Jian-an HE Hong ZHANG Xiang-lanC ZHOU Bin-quan JIANG Chen-yang |
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| Abstract: | In order to study the relation between hypertensive left ventricular hypertrophy （LVH）in the elderly with neurohormone factors and ventricular arrhythmias,measurements were made on the heart rate variation，rein（Ren），angiotensin-Ⅱ（AT-Ⅱ），aldosterone（Ald），insulin（Ins），Holter and Ambulatory blood pressure which were monitored in 120 cases of 2 groups：60 with primary hypertension in the elderly and LVH（group A）；60 with simple primary hypertension in the elderly （group B）．There was no significant difference between group AT-Ⅱ and Ren group A and group B （P＞0．05）；Ins and Ald value in group A was much higher than group B（Pall＜0．01）.Very lower frequency （VLF）,low frequency（LF）and LF／HF（high frequency）in group A were significantly higher than group B（P＜0．01，0．05，0．05，respectively）.Incidence of premature ventricular beats and myocardial ischemia in group A were higher than those in group B．From the above study we had the following findings in group A:（1）Sympathetic nerve excitability was greatly increased；（2）Hypertensive LVH were closely associated with Ald and Ins level，but not with AT-Ⅱ and Ren；（3）There was obvious connection between premature ventricular beats and ischemia． |
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| Keywords: | hypertension elderly left ventricular hypertrophy neurohumor premature ventricular beats |
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