RegIV expression showing specificity to gastrointestinal tract and its potential role in diagnosing digestive tract neuroendocrine tumor |
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| Authors: | Feng-ying LI Xiao-bin REN En-ping XU Qiong HUANG Hong-qiang SHENG Bing-jian LV Mao-de LAI |
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| Institution: | (1) Department of Endocrine Oncology, Uppsala University Hospital, Akademiska sjukhuset, 751 85 Uppsala, Sweden;(2) Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain |
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| Abstract: | Regenerating gene IV (RegIV),a member of the regenerating gene family discovered in 2001,has been found to be involved in malignancy in several different organs including the stomach,colorectum,pancreas and prostate,but the overall expression profile of RegIV has not been reported. To learn more about RegIV,we evaluated its distribution by immunohistochemistry (IHC) in a total of 360 samples including 24 types of normal tissue,40 benign and malignant lesions,and 18 neuroendocrine tumors. We found that in no... |
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| Keywords: | Colorectal cancer Expression profile Neuroendocrine tumor Regenerating gene IV (RegIV) |
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