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三种联合方案治疗轻中度高血压病疗效比较
引用本文:曾华,刘芳,梅雨珍,何咏祥.三种联合方案治疗轻中度高血压病疗效比较[J].黄冈职业技术学院学报,2012(2):89-91.
作者姓名:曾华  刘芳  梅雨珍  何咏祥
作者单位:黄冈职业技术学院医药卫生学院;黄石市第二医院
摘    要:目的比较三种二联用药方案治疗轻中度高血压病的疗效和安全性。方法随机开放对照试验,经2周安慰剂导入期,96例轻中度高血压病患者进入4周的治疗期,分三组对照用药。结果三组药物联用均能明显降低血压(P<0.01),总有效率分别为90.5%、93.6%、94.8%。结论对轻中度高血压病三种二联用药方案均安全、有效,每日一次能维持24小时降压效应,B、C组较A组为佳。

关 键 词:高血压  治疗方案  联合  硝苯地平控释片  苯那普利  比索洛尔

Comparison of the Efficacy of Three Joint Programs in the Treatment of Mild to Moderate Hypertension
ZENG Hua,LIU Fang,MEI Yu-zhen,HE Yong-xiang.Comparison of the Efficacy of Three Joint Programs in the Treatment of Mild to Moderate Hypertension[J].Journal of Huanggang Polytechnic,2012(2):89-91.
Authors:ZENG Hua  LIU Fang  MEI Yu-zhen  HE Yong-xiang
Institution:1(1.Huanggang Polytechnic College Huanggang 438000 Hubei; 2.Hubei Huangshi the 2nd Hospital,Huangshi 435000 Hubei)
Abstract:Objective: To compare the efficacy and safety of three bivalent drugs in the treatment of mild to moderate hypertension.Methods: The randomized,open controlled trial,after 2 weeks placebo in period,96 cases of mild to moderate hypertensive patients entered a 4-week treatment period,divided into three groups and controlled drugs.Results: Three groups of drugs associated use can significantly reduce blood pressure(P <0.01),the total effective rate were 90.5%,93.6%,94.8%.Conclusion: Three regimens to cure mild to moderate hypertension are safe and effective,once daily to maintain 24-hour antihypertensive effect,the group B,C are better than the A group.
Keywords:Hypertension  Treatment programs  Joint  nifedipine controlled release tablet  Benazepril  Bisoprolol
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