Acid Phosphatase as a Marker in Malaria |
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| Authors: | Benedicta D’Souza Rajeevalochana Parthasarathy Sreekantha Vivian D’Souza |
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| Institution: | (1) Department of Biochemistry, Manipal University, Centre for Basic Sciences, Kasturba Medical College, Bejai, Mangalore, 575004, India;(2) Department of Medicine, Manipal University, Kasturba Medical College, Manipal, India |
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| Abstract: | The serum acid phosphatase (ACP) activity and Hemoglobin (Hb) levels were measured in malaria patients and nonmalarial fever
patients. The results were compared with normal healthy control subjects. ACP was significantly increased (P < 0.001) in all the malaria patients. ACP was significantly higher in Plasmodium falcifarum malaria and mixed malaria when compared to Plasmodium vivax malaria. Hb levels were significantly decreased in all the malaria patients which indicates that malaria parasite uses host
erythrocyte Hb as a major nutrient source. There is negative correlation(r = −0.478) between ACP and Hb in malaria patients, which is highly significant. These results suggest that the measurement
of ACP could be used as a marker for malaria. |
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| Keywords: | Acid phosphatase Malaria Hemoglobin |
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