Colorado longitudinal twin study of reading disability |
| |
| Authors: | Sally J Wadsworth John C DeFries Richard K Olson Erik G Willcutt |
| |
| Institution: | (1) Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80309, USA;(2) Department of Psychology, University of Colorado, Boulder, CO 80309, USA |
| |
| Abstract: | The primary objectives of the present study are to introduce the Colorado Longitudinal Twin Study of Reading Disability, the
first longitudinal twin study in which subjects have been specifically selected for having a history of reading difficulties,
and to present some initial assessments of the stability of reading performance and cognitive abilities in this sample. Preliminary
examination of the test scores of 124 twins with a history of reading difficulties and 154 twins with no history of reading
difficulties indicates that over the 5- to 6-year interval between assessments, cognitive and reading performance are highly
stable. As a group, those subjects with a history of reading difficulties had substantial deficits relative to control subjects
on all measures at initial assessment, and significant deficits remained at follow-up. The stability noted for all cognitive
and achievement measures was highest for a composite measure of reading, whose average stability correlation across groups
was 0.80. Results of preliminary behavior genetic analyses for this measure indicated that shared genetic influences accounted
for 86% and 49% of the phenotypic correlations between the two assessments for twin pairs with and without reading difficulties,
respectively. In addition, genetic correlations reached unity for both groups, suggesting that the same genetic influences
are manifested at both time points. |
| |
| Keywords: | Longitudinal Twin Reading disability Cognitive ability Etiology Genetic Stability |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
