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茯苓对家兔利尿作用的观察
引用本文:宁康健,杨靖松,石萍萍.茯苓对家兔利尿作用的观察[J].安徽科技学院学报,2012,26(4):1-3.
作者姓名:宁康健  杨靖松  石萍萍
作者单位:安徽科技学院动物科学学院,安徽风阳,233100;安徽省怀远县畜牧兽医局,安徽怀远,233400
基金项目:安徽科技学院重点学科建设项目
摘    要:观察茯苓水煎醇沉液对兔的利尿作用。取雄性家兔24只随机均分Ⅳ组,兔称重全身麻醉后固定于手术台上,沿尿道口将导尿管插入膀胱内收集尿液,连续记录1h内排尿量。Ⅰ~Ⅳ组分别按0g/kg、0.5g/kg、1.5g/kg、2.5g/kg剂量耳缘静脉注射茯苓水煎醇沉液。结果:静注茯苓水煎醇沉液1.5g/kg、2.5g/kg剂量组利尿作用明显(P0.01),其中2.5g/kg剂量组在给药10min内尿量出现高峰。表明茯苓对兔具有明显的利尿作用,并且存在一定程度的正向量效关系。

关 键 词:茯苓  利尿作用  

Observation of Poria Cocos on Diuretic Effect in Rabbits
NING Kang-jian,YANG Jing-song,SHI Ping-ping.Observation of Poria Cocos on Diuretic Effect in Rabbits[J].Journal of Anhui Science and Technology University,2012,26(4):1-3.
Authors:NING Kang-jian  YANG Jing-song  SHI Ping-ping
Institution:1(1.College of Animal Science,Anhui Science and Technology University,Fengyang 233100,China; 2.Huaiyuan County Animal Husbandry and Veterinary Bureau,Huaiyuan 233400,China)
Abstract:To observe the diuretic effect of Poria cocos’ decoction and alcohol deposit fluid in rabbits.24 male rabbits were divided into 4 groups randomly.All rabbits are weighed and global anesthesia was under the operating in turn,the catheter along the urethra into the bladder to collect urine,and continuous record of urine output was done within one hour.Ⅰ~ IV groups were injected with Poria cocos’ decoction and alcohol deposit fluid from ear vein and dose at 0g/kg 0.5g/kg,1.5g/kg,2.5g/kg respectively.Result: There were significant diuretic effects(P<0.01) at intravenous 1.5g/kg,2.5g/kg dose group,and urine output peak of 2.5g/kg dose group appeared within 10min.It is indicated that the Poria cocos has obvious diuretic effect in rabbits,and its effect did appear to positive correlation with dose to some extent.
Keywords:Poria cocos  Diuretic effect  Rabbits
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