| FPN1基因多态性与HiHiLo训练后血象指标训练效果的关联性研究 |
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| 引用本文： | 乌云格日勒,胡扬,衣龙彦,聂晶,王景玲,吉洪书.FPN1基因多态性与HiHiLo训练后血象指标训练效果的关联性研究[J].北京体育大学学报,2011,34(5):48-51. |
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| 作者姓名： | 乌云格日勒 胡扬 衣龙彦 聂晶 王景玲 吉洪书 |
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| 作者单位： | 内蒙古师范大学;北京体育大学;江西师范大学;青岛体育训练基地;南京体育学院; |
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| 基金项目： | 科技部奥运攻关课题“我国优秀运动员选材用遗传标记的研究”(2006BAK12B01) |
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| 摘 要： | 目的:探讨FPN1基因多态性与HiHiLo训练效果的关联性。方法:选取70名健康受试者在模拟海拔2 800 m高度进行30 d HiHiLo训练(低氧暴露10 h/d、除白天常氧训练外,以75%.VO2max强度每周进行3次低氧训练),测定训练前、训练后第4 d、第7 d、第16 d、第23 d和第30 d的RBC、Hct和Hb等血象指标,应用PCR-RFLP方法解析基因多态性。结果:FPN1基因rs1123110和rs4145237多态性与血象指标的初始值不关联。经30 d HiHiLo训练训练后,rs1123110位点TT型RBC、Hb、Hct的平均增加量显著高于TC型;TT型Hb、Hct从第7 d、RBC从第16 d开始显著增加并持续至第30 d。rs4145237位点GG型RBC、Hb、Hct的平均增加量显著高于CG型;GG型Hb、Hct、RBC从第16 d开始显著增加,随后持续升高至第30 d。结论:rs1123110的TT型和rs4145237的GG型与HiHiLo训练效果关联,可以作为预测血象指标训练效果的分子标记。
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| 关 键 词： | 膜铁转运蛋白1 基因多态性 高住高练低训 血象指标 |
Correlative Research on the FPN1 Polymorphism and the Training Effect of the Hematology Parameters after HiHiLo Training |
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| WUYUN Gerile,HU Yang,YI Long-yan,NIE Jing,WANG Jing-ling,JI Hong-shu.Correlative Research on the FPN1 Polymorphism and the Training Effect of the Hematology Parameters after HiHiLo Training[J].Journal of Beijing Sport University,2011,34(5):48-51. |
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| Authors: | WUYUN Gerile HU Yang YI Long-yan NIE Jing WANG Jing-ling JI Hong-shu |
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| Institution: | WUYUN Gerile1,HU Yang2,YI Long-yan2,NIE Jing3,WANG Jing-ling4,JI Hong-shu5(1.College of Physical Education,Inner Mongolia Normal University,HHHOT 010022,Inner Mongolia China,2.Beijing Sport University,Beijing 100084,China,3.College of Physical Education,Jiangxi Normal University,Nanchang 330027,Jiangxi China,4.Qingdao Sport Training Center,Qingdao 266023,Shandong China,5.Nanjing Institute of Physical Education,Nanjing 210014,Jiangsu China) |
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| Abstract: | Objective: The purpose of this study was to investigate association between FPN1 gene polymorphism and effect of HiHiLo training.Methods: Seventy health subjects completed thirty-day HiHiLo program at the mock height of 2800m above the sea level(hypoxia exposure 10hr every day,trained in the hypoxic environment 3 times with 75%VO2max every week,and trained at sea level everyday),and physiological parameters,such as RBC,Hct,Hb,were tested before the training and the 4th,7th,16th,23rd,30th day after the train... |
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| Keywords: | FPN1 gene polymorphism HiHilo training Hematology Parameters |
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