Evaluation of hypoglycemic and antioxidant effect of<Emphasis Type="Italic">Ocimum sanctum</Emphasis> |
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| Authors: | Jyoti Sethi Sushma Sood Shashi Seth Anjana Talwar |
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| Institution: | (1) Department of Physiology B. D. Sharma, PGIMS, Rohtak;(2) Department of Biochemistry, Pt. B. D. Sharma, PGIMS, Rohtak;(3) C-213, Madhuvan, 110 092 Delhi |
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| Abstract: | Ocimum sanctum leaves have been traditionally used in treatment of diabetes mellitus. Dietary supplementation of fresh tulsi leaves in a
dose of 2 gm/kg BW for 30 days led to significant lowering of blood glucose levels in test group. Intake ofOcimum sanctum also led to significant increase in levels of superoxide dismutase, reduced glutathione and total thiols, but marked reduction
in peroxiodised lipid levels as compared to untreated control group. The leaves were found to possess both superoxide and
hydroxyl free radical scavenging action. The present observations establish the efficacy ofOcimum sanctum leaves in lowering blood glucose levels and antioxidant property appears to be predominantly responsible for hypoglycemic
effect. |
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| Keywords: | Ocimum sanctum hypoglycemic effect antioxidant free radical scavenger |
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