No effect of HMB or α-HICA supplementation on training-induced changes in body composition |
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| Authors: | Filipe J Teixeira Catarina N Matias Cristina P Monteiro Maria J Valamatos Joana F Reis Ana Batista |
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| Institution: | 1. Laboratory of Physiology and Biochemistry of Exercise, Faculty of Human Kinetics, Universidade de Lisboa, Cruz Quebrada, Portugal;2. Laboratory of Exercise and Health, Faculty of Human Kinetics, Universidade de Lisboa, Cruz Quebrada, Portugal;3. Interdisciplinary Center for the Study of Human Performance, Faculty of Human Kinetics, Universidade de Lisboa, Cruz Quebrada, Portugal;4. Neuromuscular Research Lab, Faculty of Human Kinetics, Universidade de Lisboa, Cruz Quebrada, Portugal;5. Universidade Europeia, Lisboa, Portugal |
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| Abstract: | β-hydroxy-β-methylbutyrate (calcium: HMB-Ca and free acid: HMB-FA) and α-hydroxyisocaproic acid (α-HICA) are leucine metabolites that have been proposed to improve body composition and strength when combined with resistance exercise training (RET). In this double-blind randomized controlled pragmatic trial, we evaluated the effects of off-the-shelf supplements: α-HICA, HMB-FA and HMB-Ca, on RET-induced changes in body composition and performance. Forty men were blocked randomized to receive α-HICA (n?=?10, fat-free mass FFM]?=?62.0?±?7.1?kg), HMB-FA (n?=?11, FFM?=?62.7?±?10.5?kg), HMB-Ca (n?=?9, FFM?=?65.6?±?10.1?kg) or placebo (PLA; n?=?10, FFM?=?64.2?±?5.7?kg). The training protocol consisted of a whole-body resistance training routine, thrice weekly for 8 weeks. Body composition was assessed by dual-energy x-ray absorptiometry (DXA) and total body water (TBW) by whole-body bioimpedance spectroscopy (BIS), both at baseline and at the end of weeks 4 and 8. Time-dependent changes were observed for increase in trunk FFM (p?
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| Keywords: | Resistance training fat-free mass leucine metabolites |
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