| RAPID DETERMINATION OF GUANINE BY HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS |
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| 作者姓名： | Zhang Shusheng |
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| 作者单位： | Zhang Shusheng
(Center of Analysis and Test，Zhengzhou University，Zhengzhou 450052)
Chen Yong Yuan Zhuobin
(Graduate School，Academia Sinica，Beijing 100039) |
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| 基金项目： | The work was supported by National Nature Science Foundation of P. R. China，by Foundation of Lab. of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,Academia Sinica |
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| 摘 要： | A simple and reproduciable method for determining guanine by high performance capillary electrophoresis is presented. The method involved the use of 2-amino-5-mercapto-3,4-dithiazole as internal standard and 40mmol/L borax-H3PO4 (pH2)-5% EtOH as.the background electrolyte. The result showed that the linear range for guanine is 5-300 mg/L with the recovery of 94%-98% , the detection limit of 2. 80 mg/L and the RSD of 3. 1%. The satisfactory result was obtained when it was used to detect the concentration of guanine in acyclovir product.
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RAPID DETERMINATION OF GUANINE BY HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS |
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| Zhang Shusheng.RAPID DETERMINATION OF GUANINE BY HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS[J].Journal of the Graduate School of the Chinese Academy of Sciences,1997(1). |
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| Authors: | Zhang Shusheng |
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| Abstract: | A simple and reproduciable method for determining guanine by high performance capillary electrophoresis is presented. The method involved the use of 2-amino-5-mercapto-3,4-dithiazole as internal standard and 40mmol/L borax-H3PO4 (pH2)-5% EtOH as.the background electrolyte. The result showed that the linear range for guanine is 5-300 mg/L with the recovery of 94%-98% , the detection limit of 2. 80 mg/L and the RSD of 3. 1%. The satisfactory result was obtained when it was used to detect the concentration of guanine in acyclovir product. |
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| Keywords: | high performance capillary electrophoresis guanine determination |
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