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| 运动过程中骨骼肌摄取葡萄糖的调节 | |
| 引用本文： | 周亮,杨则宜,魏源.运动过程中骨骼肌摄取葡萄糖的调节[J].体育科学,2006,26(5):69-73. |
| 作者姓名： | 周亮 杨则宜 魏源 |
| 作者单位： | 1. 北京体育大学,北京,100084 2. 国家体育总局运动医学研究所,北京,100029 3. 广州体育学院,广东,广州,510006 |
| 摘 要： | 运动过程骨骼肌摄取葡萄糖的速率主要受到3个因素的影响：葡萄糖运送到肌细胞的速率、肌细胞膜对葡萄糖的转运速率以厦肌细胞内对葡萄糖的磷酸化。细胞膜对葡萄糖的转运相对于葡萄糖的运输和磷酸化显得更为重要。运动时会出现肌细胞膜上GLUT4的转位并增加时葡萄糖的转运，但其机制并不是很清楚，很有可能是通过细胞内的一些分子信号传递，这些信号包括：CaMK，PKC，NO，AMPK，PKB和aPKC等。 |
| 关 键 词： | 运动 葡萄糖 蛋白激酶C 一氧化氮 AMP激活的蛋白激酶 蛋白激酶B 非特异性蛋白激酶C |
| 文章编号： | 1000-677X（2006）05-0069-05 |
| 收稿时间： | 2005-12-15 |
| 修稿时间： | 2005-12-152006-03-30 |
Regulation on Muscle Glucose Uptake during Exercise |
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| ZHOU Liang,YANG Ze-yi,WEI Yuan.Regulation on Muscle Glucose Uptake during Exercise[J].China Sport Science,2006,26(5):69-73. | |
| Authors: | ZHOU Liang YANG Ze-yi WEI Yuan |
| Institution: | 1. Beijing Sport University, Beijing 100084; 2. Research Institute of Sports 100029, China; 3. Guangzhou Sports 510006,China. Medicine, China Beijing College ,Guangzhou |
| Abstract: | The velocity of muscle glucose uptake during exercise was affected by three factors, the rate of glucose delivering to celts,glucose transport into cells and glucose phosphorylated within the cells. Membrane glucose transport was more important than delivery and phosphorylation. GLUT-4 translocation at muscle membrane during exercise increased the transport of glucose, but mechanism was unclear. It was likely to occur through intracellular signaling involving CaMk,PKC,NO,AMPK,PKB and aPKC. |
| Keywords: | ewercise glucose PKC NO AMPK PKB aPKC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |