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中国雷公藤制剂治疗系统性红斑狼疮疗效的Meta分析
引用本文:唐宁,周红霞,周东蕊.中国雷公藤制剂治疗系统性红斑狼疮疗效的Meta分析[J].南京晓庄学院学报,2012(3):68-71.
作者姓名:唐宁  周红霞  周东蕊
作者单位:南京晓庄学院生物化工与环境工程学院,江苏南京,211171
基金项目:国家自然科学研究基金资助项目
摘    要:应用Cochrne协作网和保存系统评价的专用分析软件RevMan4.2进行Meta分析,对1982年至今我国公开发表的运用雷公藤制剂辅助或联合其他药物治疗系统性红斑狼疮的文献进行临床疗效的综合评价分析.结果表明,符合并纳入该次Meta分析的文献共有九篇,经卡方检验OR=0.26(95%CI为0.16~0.40),OR值大于零,且"漏斗图"图形基本对称并偏向对照组,表明雷公藤制剂治疗系统性红斑狼疮有较为明显的效果.

关 键 词:雷公藤  系统性红斑狼疮  疗效  meta分析

Meta Analysis on Efficacy of Preparations of Tripterygium in Treating Systemic Lupus Erythematosus
TANG Ning,ZHOU Hong-xia,ZHOU Dong-rui.Meta Analysis on Efficacy of Preparations of Tripterygium in Treating Systemic Lupus Erythematosus[J].Journal of Nanjing Xiaozhuang College,2012(3):68-71.
Authors:TANG Ning  ZHOU Hong-xia  ZHOU Dong-rui
Institution:(School of Biochemistry and Environmental Engineering,Nanjing Xiaozhuang University,Nanjing 211171,Jiangsu)
Abstract:In the present study,meta analysis is conducted with the use of Cochrne cooperative network and the specialized analysis software RevMan4.2 for preserving systematic evaluation,aiming at the synthetical evaluation and the analysis of full-text documents published in China from 1982 up to now concerning the use of Mongolian gerbilsin either to assist the treatment of or to be combined with other drugs to treat systemic lupus erythemalosus.The results show that there are nine of the documents which are consistent with and included in this meta analysis method.The synthesized analysis results indicate that the OR is 0.26(95 %CI,0.16—0.40),which is greater than zero visible.It can clearly be seen that Mongolian gerbilsin has played a certain role in the treatment of systemic lupus erythemalosus.
Keywords:tripterygium wilfordii  systemic lupus erythemalosus  curative effect analysis  meta analysis
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