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Committee on science and the arts
Authors:John Frazer
Abstract:In contradiction to results previously reported, it has been found that DNA prepared by a method which utilizes strong NaOH is acted on by the specific nuclease, although at a rate only 20 per cent. of that of DNA prepared by a milder method. The nature of the changes responsible for the low rate of hydrolysis of the alkali-treated DNA are not known.
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