Hypogonadotropic Hypogonadism and Gynaecomastia in the Young Adult: A Case Series |
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| Authors: | Moushumi Lodh Rajarshi Mukhopadhyay |
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| Institution: | 1.The Mission Hospital,Durgapur,India;2.Department of Endocrinology,The Mission Hospital,Durgapur,India |
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| Abstract: | We present three cases who presented to our Endocrinology OPD a few days apart with the common complaints of no or minimal development of secondary sexual characteristics. Although they had similar problems, investigations revealed a spectrum of different clinical, biochemical and genetic abnormalities. All the patients had otherwise normal anterior pituitary hormone secretion and sellar anatomy. One had a short Y chromosome, one was a Klinefelter syndrome and the other had no chromosomal abnormality. These findings along with absence of any detectable abnormality on pituitary imaging helped us diagnose these cases as Idiopathic hypogonadotropic hypogonadism. Treatment with testosterone showed marked improvement at 1 year follow up. |
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| Keywords: | Male infertility Hypogonadism Endocrine system abnormalities Gynaecomastia Testosterone Azoospermia |
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