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Some oxidative stress related parameters in patients with head and neck carcinoma
Authors:Nisha  Ashuma Sachdeva  Harbans Lal
Institution:(1) Department of Biochemistry, Pt. B.D.Sharma, Post Graduate Institute of Medical Sciences, 15/8 FM, PGIMS, Rohtak, 124001, Haryana, India
Abstract:Forty cases of head and neck cancer were studied for plasma superoxide dismutase, malondialdehyde and thiol levels and results were compared with a group of forty normal healthy volunteers. Mean plasma superoxide dismutase activity was not found to be altered while malondialdehyde concentration was significantly higher when compared with the control group. On the other hand, mean thiol level was significantly lowered. The data suggests increased level of oxidative stress in patients with head and neck cancer.
Keywords:Head and neck carcinoma  Oxidative stress  Antioxidants  Superoxide dismutase  Malondialdehyde  Thiol
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