| 3-氨基丁烯酸甲酯的合成研究 |
| |
| 引用本文： | 于海军,马计东,李立琴,刘彦辉.3-氨基丁烯酸甲酯的合成研究[J].石家庄职业技术学院学报,2012,24(6):5-8. |
| |
| 作者姓名： | 于海军 马计东 李立琴 刘彦辉 |
| |
| 作者单位： | 1. 石家庄职业技术学院化学工程系,河北石家庄,050081
2. 石家庄合佳保健品有限公司生产部,河北石家庄,050000 |
| |
| 摘 要： | 研究了利用乙酰乙酸甲酯、氨基甲酸铵制备3-丁烯酸甲酯的方法,反应收率95.43%,但投料比、蒸馏方式、原料均对反应的收率和纯度有影响.反应的后续蒸馏不仅可以回收溶剂,同时可以回收反应体系中的副产物碳酸氢铵.此方法反应时间短,无污染,分离简便,产品收率高、纯度好.
|
| 关 键 词： | 3-氨基丁烯酸甲酯 乙酰乙酸甲酯 氨基甲酸铵 |
The synthesis of methyl 3-aminocroton |
| |
| YU Hai-jun MA Ji-dong LI Li-qin,LIU Yan-hui.The synthesis of methyl 3-aminocroton[J].Journal of Shijiazhuang Vocational Technology Institute,2012,24(6):5-8. |
| |
| Authors: | YU Hai-jun MA Ji-dong LI Li-qin LIU Yan-hui |
| |
| Institution: | 1. Department of Chemistry,Shijiazhuang Vocational Technology Institute, Shijiazhuang, Hebei 050081,China; 2. Department of Production, Shijiazhuang Hejia Health Productions Co. Ltd, Shijiazhuang, Hebei 050000,China) |
| |
| Abstract: | A novel method is introduced on the synthesis of methyl 3-aminocrotonate by methyl aceto- acetate with ammonium carbamate. The yield rate is 95.43%. The feed ratio,distillation and raw materials take effect on reaction and product purity. The subsequent distillation recycles solvents, and restores the by-product ammonium hydrogen carbonate during reaction. This method enjoys shorter reaction time,no pollution, easy separation, high yield and good purity. |
| |
| Keywords: | methyl 3-aminocrotonate~ methyl acetoacetate ammmonium carbamate |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
