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| 新型胡椒醛基氮杂环丙基二正丙基三级醇手性配体的合成与表征 | |
| 引用本文： | 王瑾,刘冠军,张朋飞,赵瑞娟,孔伟光,赵文献.新型胡椒醛基氮杂环丙基二正丙基三级醇手性配体的合成与表征[J].商丘师范学院学报,2012,28(9):45-48. |
| 作者姓名： | 王瑾 刘冠军 张朋飞 赵瑞娟 孔伟光 赵文献 |
| 作者单位： | 1. 郑州大学化学与分子工程学院,河南郑州,450052 2. 商丘师范学院化学化工学院,商丘师范学院有机新材料合成重点实验室,河南商丘476000 3. 商丘师范学院化学化工学院,商丘师范学院有机新材料合成重点实验室,河南商丘476000 郑州大学化学与分子工程学院,河南郑州450052 |
| 基金项目： | 国家自然科学基金(20972091,21172193)资助项目;河南省科技攻关项目(092102210121);商丘师范学院博士科研启动基金支持项目 |
| 摘 要： | 以L-丝氨酸为原料,经酯化、缩合、还原氨化、关环等反应,得到一种新型的胡椒醛基氮杂环丙基羧酸酯,再与格氏试剂反应,高效地得到一种新型的胡椒醛基氮杂环丙基二正丙基三级醇手性配体,产物结构通过IR、1H NMR、13C NMR和HRMS表征确定. |
| 关 键 词： | 胡椒醛 β-氨基醇 不对称合成 手性配体 |
Synthesis and characterization of a new piperonyl aziridino dipropyl tertiary alcohol chiral ligands |
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| WANG Jin,LIU Guanjun,ZHANG Pengfei,ZHAO Ruijuan,KONG Weiguang,ZHAO Wenxian.Synthesis and characterization of a new piperonyl aziridino dipropyl tertiary alcohol chiral ligands[J].Journal of Shangqiu Teachers College,2012,28(9):45-48. | |
| Authors: | WANG Jin LIU Guanjun ZHANG Pengfei ZHAO Ruijuan KONG Weiguang ZHAO Wenxian |
| Institution: | 1,2(1.Department of Chemistry and Chemical Engineering and Key Laboratory of New Organic Materials Synthesis, Shangqiu Normal University,Shangqiu 476000,China;2.Department of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou 450052,China) |
| Abstract: | A new piperonyl aziridino carboxylic acid ester is synthesized by means of esterification,condensation,reductive amination and ringclosure from L-serine,then reaction with Grignard reagent,provide a new piperonyl aziridino dipropyl tertiary alcohol chiral ligand with high yield.The structure of the product was confirmed by IR,1H NMR,13C NMR and HRMS. |
| Keywords: | piperonal β-amino alcohol asymmetric synthesis chiral ligand |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |