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并、缺指畸形胎儿指皮的组织学观察与比较
引用本文:陈军芳,张明军,景玉萍,郑建国.并、缺指畸形胎儿指皮的组织学观察与比较[J].孝感职业技术学院学报,2006,9(4):100-102.
作者姓名:陈军芳  张明军  景玉萍  郑建国
作者单位:湖北职业技术学院,医学院,湖北,孝感,432000 湖北职业技术学院,医学院,湖北,孝感,432000 湖北职业技术学院,医学院,湖北,孝感,432000 湖北职业技术学院,医学院,湖北,孝感,432000
摘    要:目的:探讨并、缺指畸形胎儿指皮组织学结构与正常胎儿结构的差异.方法:观察并、缺指畸形胎儿大体形态,常规取材,HE染色,通过光学显微镜观察指皮组织学结构.结果:并、缺指畸形胎儿镜下观察指皮分层及附属结构与正常胎儿相似,但表皮颗粒层和棘层内朗格汉斯细胞比正常胎儿明显增多,未见触觉小体和环层小体.结论:并、缺指畸形胎儿的致畸因子可能影响其感觉神经末梢的发育和成熟,朗格汉斯细胞增多可能是遗传因素的作用或环境影响所致.

关 键 词:并、缺指畸形  指皮  朗格汉斯细胞  感觉神经末梢
文章编号:1671-8178(2006)04-0100-03
修稿时间:2006年11月8日

The Histological Observation and Comparison of the Finger Skin of Syndactly and Sxtrodactyly Foetus
CHEN Jun-fang,ZHANG Ming-jun,JING Yu-ping,ZHENG Jian-guo.The Histological Observation and Comparison of the Finger Skin of Syndactly and Sxtrodactyly Foetus[J].Journal of Xiaogan Vocational-Technical College,2006,9(4):100-102.
Authors:CHEN Jun-fang  ZHANG Ming-jun  JING Yu-ping  ZHENG Jian-guo
Abstract:Purpose: To discuss the differences of the histological structure of finger skin between syndactly and extrodactyly foetus and normal foetus.Method: To observe the configuration of syndactly and extrodactyly foetus,draw materials generally,then dye with the methods of H.E,finally observe the finger skin histological structure under the light microscope.Result: The study shows that the finger epidermis delamination and accessorial structure of syndactly and extrodactyly foetus resembles normal foetus,but the quantities of Langerhans cell in the stratum granulosum and stratum spinosum of epidermis are obviously more than those in normal foetus,and can't find tactile corpuscle and lamellar corpuscle.Conclusion: The teratogen of syndactly and extrodactyly foetus possibly influences the development and maturation of sensory nerve ending.Genetic factor or environmental influence possibly conduces to the increase of Langerhans cell.
Keywords:syndactyly and extrodactyly  the finger skin  Langerhans cell  sensory nerve ending
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