| 冠心病患者颈动脉粥样硬化与血管内皮舒张功能的临床研究 |
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| 引用本文： | 王义成,袁桂莉,赵九安.冠心病患者颈动脉粥样硬化与血管内皮舒张功能的临床研究[J].河北北方学院学报(医学版),2007,24(1):9-11. |
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| 作者姓名： | 王义成 袁桂莉 赵九安 |
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| 作者单位： | 1. 河北北方学院附属第一医院超声科,河北,张家口,075000
2. 河北北方学院附属第一医院心内科,河北,张家口,075000 |
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| 基金项目： | 河北省科学技术研究与发展计划 |
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| 摘 要： | 目的：研究冠心病患者颈动脉粥样硬化与血管内皮舒张功能的临床意义。方法：采用高频超声测量冠心病组和对照组颈动脉斑块积分、斑块数、颈动脉内-中膜厚度（IMT）及血管内皮舒张功能（EDD％），并进行对比分析。结果：1．冠心病组颈动脉IMT、斑块积分及斑块数明显高于对照组，多支冠脉血管病变组明显高于单支病变组；2．冠心病组内皮舒张功能明显低于对照组，单支、双支病变组间无显著性差异。3．冠状动脉造影与颈动脉超声结果比较，以斑块存在为预测冠脉病变的阳性指标，敏感性为83％、特异性75％。结论：冠心病患者多合并血管舒张功能受损及颈动脉粥样硬化，高频超声探查颈动脉可预测冠状动脉病变的存在及严重程度。
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| 关 键 词： | 冠心病 血管内皮舒张功能 颈动脉粥样硬化 |
| 文章编号： | 1673-1484(2007)01-0009-03 |
Clinical Study on Carotid Arterosclerosis and Endothelium-dependent Dilation in Coronary Heart Disease |
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| WANG Yi-cheng,YUAN Gui-li,ZHAO Jiu-an.Clinical Study on Carotid Arterosclerosis and Endothelium-dependent Dilation in Coronary Heart Disease[J].Journal of Hebei North University:Medical Edition,2007,24(1):9-11. |
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| Authors: | WANG Yi-cheng YUAN Gui-li ZHAO Jiu-an |
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| Abstract: | Objective: To investigate the clinical significance of the carotid arterosclerosis and endothelium-dependent dilation(EDD%) in coronary heart disease.Methods: The intima-media thickness(IMT),Crouse scores and numbers of plaque in carotid artery and endothelium-dependent dilation were measured by high-frequency ultrasound in patients with coronary artery disease and control group.The rersults were analyzed and compared.Results: There were significant differences in carotid artery IMT value,Crouse scores and numbers of plaque among the control,one-vessel stenosis and multi-vessel stenosis groups.There were significant differences in EDD% between control group and coronary artery disease group.There was no difference between one-vessel stenosis and multi-vessel stenosis groups.The sensitivity and specificity of predicting the coronary artery atherocslerosis by the carotid plaque were 83% and 75%.Conclusion: Carotid artery atherosclerosic lesions and EDD% can predict the existence and severity of the coronary artery atherosclerosis. |
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| Keywords: | Coronary heart disease Endothelium-dependent Dilation Carotid arterosclerosis |
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