Application of Tucatinib and Trastuzumab: Dual Anti HER2 Therapy Against HER2 Positive Breast Cancer |
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| Authors: | Sumanpreet Kaur Rajasri Bhattacharyya Dibyajyoti Banerjee Jaya Shukla |
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| Institution: | 1.Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh, 160012 India ;2.Department of Nuclear Medicine, PGIMER, Chandigarh, 160012 India |
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| Abstract: | Synergism in action of tucatinib and trastumab is reported in breast cancer management. However, its molecular basis is yet to be determined. In this context we attempted to provide an explanation at the molecular level by performing in silico experimentation and coupling its result with already available published observations. Our study will provide basis for planning further experimental study for unravelling the truth. |
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| Keywords: | Tucatinib Trastumab Synergism Breast cancer |
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