| 骨性关节炎的运动相关实验追踪 |
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| 引用本文： | 赵福临,刘奇才.骨性关节炎的运动相关实验追踪[J].福建体育科技,2008,27(1):31-32. |
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| 作者姓名： | 赵福临 刘奇才 |
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| 作者单位： | 1. 福建医科大学体育教研部,福建,闽候,350108
2. 福建医科大学基因诊断研究室 |
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| 摘 要： | 目的：探讨运动性的骨性关节炎发病机制及其实验室指标的变化情况。方法：对80例长跑爱好者进行分组，其中影象学或症状提示骨性关节炎的18例，对照62例，检测所有受试者的蛋白多糖含量，并对骨性关节炎患者进行抗环状胍氨酸多肽抗体（CCP）检测。结果：骨性关节炎患者的蛋白糖、IgA、IgG和补体C3明显较对照组显著性差异（P〈0．05），6／18的骨性关节炎患者中可以检测到抗环状胍氨酸多肽抗体。结论：关节软骨中蛋白多糖含量下降是造成关节软骨破坏、形成骨性关节炎的重要因素。
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| 关 键 词： | 骨性关节炎 蛋白多糖 抗环状胍氨酸多肽抗体 |
| 文章编号： | 1004-8790(2008)01-0031-02 |
Osteoarthritic Exercise Related Laboratory Target |
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| Zhao Fu-lin.Osteoarthritic Exercise Related Laboratory Target[J].Fujian Sports Science and Technology,2008,27(1):31-32. |
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| Authors: | Zhao Fu-lin |
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| Institution: | Zhao Fu- linet al (Fujian Medical University, Fuzhou 350108, China) |
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| Abstract: | Objective:Discuss the pathogenesis and the changing laboratory target of the mobile osteoarthritis.Methods:Groups 80 examples long-distance-runner into two groups,the 18 examples of which diagnosed as osteoarthritis by the imaging or symptomatology is divided into the case group,on the contrast the other 62 examples not diagnosed as osteoarthritis is divided into the comparable group. Detect proteoglycan content in all the testees and CCP to the osteoarthritic patients.Result:The proteoglycan,IgA,IgG and C3 of the osteoarthritic patients are obviously significant different from the comparison(P<0.05)6/18 of the osteoarthritic patients may be detected in CCP.Conclusion:The drop of the articular cartilage proteoglycan content is an important attribute of creating the articular cartilage to destroy,to form the osteoarthritis. |
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| Keywords: | Osteoarthritis Proteoglycan CCP |
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